Pigs offer a potentially plentiful supply of organs for humans, but widespread xenotransplantation will require a collaborative and iterative approach to research, as well as involvement of transplant patients and the public.
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Acknowledgements
We acknowledge J. Stern, B. Lonze, G. Piper, Z. Stuart-Lewis, E. Weldon and B. Sullivan for their invaluable contributions to the xenotransplantation studies performed on decedents.
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R.A.M., S.A.M., B.P. and A.G. contributed to writing and editing the manuscript.
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R.A.M. receives research support from Lung Biotechnology, a wholly owned subsidiary of United Therapeutics, and has served as a consultant for eGenesis and Recombinetics.
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Montgomery, R.A., Mehta, S.A., Parent, B. et al. Next steps for the xenotransplantation of pig organs into humans. Nat Med 28, 1533–1536 (2022). https://doi.org/10.1038/s41591-022-01896-y
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DOI: https://doi.org/10.1038/s41591-022-01896-y
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