Skip to main content
SpringerLink
Log in

Bibliometric analysis of the top 100 most-cited articles on the treatment of osteoporosis

  • Original Article
  • Published:
Archives of Osteoporosis Aims and scope Submit manuscript

Abstract

Purpose

To perform a bibliometric analysis of the top 100 (T100) most-cited articles on the treatment of osteoporosis published between 1980 and 2021 to reveal major developments and trends in the field and to contribute to the methodologies and hypotheses of future studies.

Methods

On 15.12.2021, a search was conducted on the Web of Science database using the keyword “osteoporosis treatment” to screen articles published between 1980 and 2021. The title of the article, year of publication, total number and names of the authors, total number of citations and citation index, name and Q index of the journals, H-index, impact factor, country of authors, types of articles, and sources of funding were recorded.

Results

The most-cited article was “Osteoporosis Prevention, Diagnosis, And Therapy.” The article with the highest citation index was “Clinician’s Guide to Prevention and Treatment of Osteoporosis.. The majority of the articles were randomized controlled clinical trials. The journal with the highest number of articles included in the T100 was The New England Journal of Medicine, with 19 articles. The USA had the highest number of articles. There was a strong correlation between the number of citations and citation index of articles (p < 0.001).

Conclusions

This study, which examined the T100 most-cited articles on the treatment of osteoporosis, found that the articles primarily focused on the prevention, diagnosis, and follow-up of osteoporosis; search for antiresorptive and anabolic pharmacological agents; investigation of the efficacy and reliability of these agents on specific subpopulations; and surgical treatment options.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Suzan V, Bektan Kanat B, Yavuzer H, Doventas A (2021) Themes and trends for osteoporosis: the bibliometric and altmetric approach. Arch Osteoporos 16:122. https://doi.org/10.1007/s11657-021-00983-w

    Article  PubMed  Google Scholar 

  2. Pouresmaeili F, Kamalidehghan B, Kamarehei M, Goh YM (2018) A comprehensive overview on osteoporosis and its risk factors. Ther Clin Risk Manag 14:2029–2049. https://doi.org/10.2147/TCRM.S138000

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Tella SH, Gallagher JC (2014) Prevention and treatment of postmenopausal osteoporosis. J Steroid Biochem Mol Biol 142:155–170. https://doi.org/10.1016/j.jsbmb.2013.09.008

    Article  CAS  PubMed  Google Scholar 

  4. Sözen T, Özışık L, Başaran NÇ (2017) An overview and management of osteoporosis. Eur J Rheumatol 4:46–56. https://doi.org/10.5152/eurjrheum.2016.048

    Article  PubMed  Google Scholar 

  5. Ellegaard O, Wallin JA (2015) The bibliometric analysis of scholarly production: how great is the impact? Scientometrics 105:1809–1831. https://doi.org/10.1007/s11192-015-1645-z

    Article  PubMed  PubMed Central  Google Scholar 

  6. Ho Y-S (2012) Top-cited articles in chemical engineering in science citation index expanded: a bibliometric analysis. Chin J Chem Eng 20:478–488. https://doi.org/10.1016/S1004-9541(11)60209-7

    Article  CAS  Google Scholar 

  7. Publications impact indexes. In: Mondragon Unibertsitatea. https://www.mondragon.edu/en/web/biblioteka/publications-impact-indexes. Accessed 25 Jun 2022

  8. Qiu Y, Yang W, Wang Q et al (2018) Osteoporosis in postmenopausal women in this decade: a bibliometric assessment of current research and future hotspots. Arch Osteoporos 13:121. https://doi.org/10.1007/s11657-018-0534-5

    Article  PubMed  Google Scholar 

  9. Gao Q, Zhang C, Wang J et al (2020) The top 100 highly cited articles on osteoporosis from 1990 to 2019: a bibliometric and visualized analysis. Arch Osteoporos 15, 144. https://doi.org/10.1007/s11657-020-0705-z

  10. Osteoporosis is a neglected health priority in Arab World: a comparative bibliometric analysis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141069/. Accessed 31 Jan 2022

  11. Wu H, Sun Z, Tong L et al (2021) Bibliometric analysis of global research trends on male osteoporosis: a neglected field deserves more attention. Arch Osteoporos 16:154. https://doi.org/10.1007/s11657-021-01016-2

    Article  PubMed  Google Scholar 

  12. Brüggmann D, Mäule L-S, Klingelhöfer D et al (2016) World-wide architecture of osteoporosis research: density-equalizing mapping studies and gender analysis. Climacteric J Int Menopause Soc 19:463–470. https://doi.org/10.1080/13697137.2016.1200548

    Article  Google Scholar 

  13. Zhou S, Tao Z, Zhu Y, Tao L (2019) Mapping theme trends and recognizing hot spots in postmenopausal osteoporosis research: a bibliometric analysis. PeerJ 7:e8145. https://doi.org/10.7717/peerj.8145

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Wu H, Cheng K, Guo Q et al (2021) Mapping knowledge structure and themes trends of osteoporosis in rheumatoid arthritis: a bibliometric analysis. Front Med 8:787228. https://doi.org/10.3389/fmed.2021.787228

    Article  Google Scholar 

  15. Yun L, Wang L, Pan Y et al (2021) Current status and development trend of miRNAs in osteoporosis-related research: a bibliometric analysis. Folia Histochem Cytobiol 59:203–211. https://doi.org/10.5603/FHC.a2021.0024

    Article  CAS  PubMed  Google Scholar 

  16. Shahid I, Motiani V, Siddiqi TJ et al (2020) Characteristics of highly cited articles in heart failure: a bibliometric analysis. Future Cardiol 16:189–197. https://doi.org/10.2217/fca-2019-0016

    Article  CAS  PubMed  Google Scholar 

  17. Held M, Castelein S, Bruins M-F et al (2018) Most influential literature in spinal tuberculosis: a global disease without global evidence. Glob Spine J 8:84–94. https://doi.org/10.1177/2192568217707182

    Article  Google Scholar 

  18. Yin X, Cheng F, Wang X et al (2019) Top 100 cited articles on rheumatoid arthritis: a bibliometric analysis. Medicine (Baltimore) 98:e14523. https://doi.org/10.1097/MD.0000000000014523

    Article  PubMed  Google Scholar 

  19. Neer RM, Arnaud CD, Zanchetta JR et al (2001) Effect of parathyroid hormone (1–34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 344:1434–1441. https://doi.org/10.1056/NEJM200105103441904

    Article  CAS  PubMed  Google Scholar 

  20. NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy (2001) Osteoporosis prevention, diagnosis, and therapy. JAMA 285:785–795. https://doi.org/10.1001/jama.285.6.785

    Article  Google Scholar 

  21. Cosman F, de Beur SJ, LeBoff MS et al (2014) Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA 25:2359–2381. https://doi.org/10.1007/s00198-014-2794-

    Article  CAS  Google Scholar 

  22. Kanis JA, Cooper C, Rizzoli R et al (2019) European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA 30:3–44. https://doi.org/10.1007/s00198-018-4704-5

    Article  CAS  Google Scholar 

  23. Bone and joint health national action week - October 12–18, 2022 - National Today. https://nationaltoday.com/bone-and-joint-health-national-action-week/. Accessed 31 Dec 2021

  24. Harris ST, Watts NB, Jackson RD et al (1993) Four-year study of intermittent cyclic etidronate treatment of postmenopausal osteoporosis: three years of blinded therapy followed by one year of open therapy. Am J Med 95:557–567. https://doi.org/10.1016/0002-9343(93)90350-x

    Article  CAS  PubMed  Google Scholar 

  25. Black DM, Bilezikian JP, Ensrud KE et al (2005) One year of alendronate after one year of parathyroid hormone (1–84) for osteoporosis. N Engl J Med 353:555–565. https://doi.org/10.1056/NEJMoa050336

    Article  CAS  PubMed  Google Scholar 

  26. Black DM, Thompson DE, Bauer DC et al (2000) Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group. J Clin Endocrinol Metab 85:4118–4124. https://doi.org/10.1210/jcem.85.11.6953

    Article  CAS  PubMed  Google Scholar 

  27. Black DM, Schwartz AV, Ensrud KE et al (2006) Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA 296:2927–2938. https://doi.org/10.1001/jama.296.24.2927

    Article  CAS  PubMed  Google Scholar 

  28. Lane NE, Sanchez S, Modin GW et al (1998) Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial. J Clin Invest 102:1627–1633. https://doi.org/10.1172/JCI3914

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Brookes BC (1969) Bradford’s law and the bibliography of science. Nature 224:953–956. https://doi.org/10.1038/224953a0

    Article  CAS  PubMed  Google Scholar 

  30. Bağcıer F (2021) Top 100 cited articles on fibromyalgia syndrome: a bibliometric and altmetric analyses study. Ağrı - J Turk Soc Algol. https://doi.org/10.14744/agri.2021.53189

  31. Fisher JE, Rogers MJ, Halasy JM et al (1999) Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. Proc Natl Acad Sci 96:133–138. https://doi.org/10.1073/pnas.96.1.133

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  32. Orwoll E, Ettinger M, Weiss S et al (2000) Alendronate for the treatment of osteoporosis in men. N Engl J Med 343:604–610. https://doi.org/10.1056/NEJM200008313430902

    Article  CAS  PubMed  Google Scholar 

  33. Schnitzer T, Bone HG, Crepaldi G et al (2000) Therapeutic equivalence of alendronate 70 mg once-weekly and alendronate 10 mg daily in the treatment of osteoporosis. Alendronate Once-Weekly Study Group. Aging Milan Italy 12:1–12

    CAS  PubMed  Google Scholar 

  34. Tonino RP, Meunier PJ, Emkey R et al (2000) Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III Osteoporosis Treatment Study Group. J Clin Endocrinol Metab 85:3109–3115. https://doi.org/10.1210/jcem.85.9.6777

    Article  CAS  PubMed  Google Scholar 

  35. Kurland ES, Cosman F, McMahon DJ et al (2000) Parathyroid hormone as a therapy for idiopathic osteoporosis in men: effects on bone mineral density and bone markers. J Clin Endocrinol Metab 85:3069–3076. https://doi.org/10.1210/jcem.85.9.6818

    Article  CAS  PubMed  Google Scholar 

  36. Dempster DW, Cosman F, Kurland ES et al (2001) Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: a paired biopsy study. J Bone Miner Res Off J Am Soc Bone Miner Res 16:1846–1853. https://doi.org/10.1359/jbmr.2001.16.10.1846

    Article  CAS  Google Scholar 

  37. Reid IR (1998) Glucocorticoid-induced osteoporosis: assessment and treatment. J Clin Densitom 1:65–73. https://doi.org/10.1385/JCD:1:1:65

    Article  CAS  PubMed  Google Scholar 

  38. Manolagas SC, Weinstein RS (1999) New developments in the pathogenesis and treatment of steroid-induced osteoporosis. J Bone Miner Res Off J Am Soc Bone Miner Res 14:1061–1066. https://doi.org/10.1359/jbmr.1999.14.7.1061

    Article  CAS  Google Scholar 

  39. Garfin SR, Yuan HA, Reiley MA (2001) New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine 26:1511–1515. https://doi.org/10.1097/00007632-200107150-00002

    Article  CAS  PubMed  Google Scholar 

  40. Cortet B, Cotten A, Boutry N et al (1999) Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures: an open prospective study. J Rheumatol 26:2222–2228

    CAS  PubMed  Google Scholar 

  41. Heini PF, Wälchli B, Berlemann U (2000) Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. A prospective study for the treatment of osteoporotic compression fractures. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 9:445–450. https://doi.org/10.1007/s005860000182

    Article  CAS  Google Scholar 

  42. Ensrud KE, Crandall CJ (2017) Osteoporosis. Ann Intern Med 167:ITC17–ITC32. https://doi.org/10.7326/AITC201708010

  43. Rashki Kemmak A, Rezapour A, Jahangiri R et al (2020) Economic burden of osteoporosis in the world: a systematic review. Med J Islam Repub Iran 34:154. https://doi.org/10.34171/mjiri.34.154

  44. A bibliometric analysis of fragility fractures: top 50 - PubMed. https://pubmed.ncbi.nlm.nih.gov/34205638/. Accessed 11 Jan 2022

  45. Ballane G, Cauley JA, Luckey MM, Fuleihan GE-H (2014) Secular trends in hip fractures worldwide: opposing trends east versus west. J Bone Miner Res 29:1745–1755. https://doi.org/10.1002/jbmr.2218

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Clinic of Physical Medicine and Rehabilitation, Üsküdar State Hospital, İstanbul, Turkey

    Mustafa Hüseyin Temel

  2. Clinic of Physical Medicine and Rehabilitation, Başakşehir Çam Ve Sakura City Hospital, İstanbul, Turkey

    İbrahim Halil Erdem & Fatih Bağcıer

  3. Department of Physical Medicine and Rehabilitation, Erzurum Ataturk University, Erzurum, Turkey

    Ayhan Kul

Authors
  1. Mustafa Hüseyin Temel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. İbrahim Halil Erdem
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ayhan Kul
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Fatih Bağcıer
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Mustafa Hüseyin Temel.

Ethics declarations

Ethical statement

No ethical committee approval was required because the data used in this study were obtained from published articles.

Conflicts of interest

None.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 24 KB)

Supplementary file2 (JPG 53 KB)

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Temel, M.H., Erdem, İ.H., Kul, A. et al. Bibliometric analysis of the top 100 most-cited articles on the treatment of osteoporosis. Arch Osteoporos 17, 106 (2022). https://doi.org/10.1007/s11657-022-01141-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11657-022-01141-6

Keywords

Search

Navigation