A planar micro rotary actuator for endoscopic optical scanning

https://doi.org/10.1016/j.sna.2022.113768Get rights and content

Highlights

  • Electromagnetic micro rotary actuator developed for distal side-viewing endoscopy.

  • Planar architecture and ferrofluid bearing of the actuator allow for downsizing.

  • The actuator offers a wide range of rotation speeds to enable multimodal imaging.

  • Scanner’s hollow design with micro mirror achieves 360° viewing with no blind spot.

  • Prototype rotating a laser shows its feasibility as a distal endoscopic scanner.

Abstract

Optical endoscopy is an essential technique for diagnosing disease in modern medicine. Side-viewing endoscopic probes with an embedded distal actuator that circumferentially scans an imaging light within an organ’s lumen are expected to significantly enhance the imaging ability of the probes. To this end, this work develops and experimentally analyzes an electromagnetic micro rotary actuator with a planar and hollow architecture. The actuator uses a liquid-phase bearing based on ferrofluid that is self-sustained on the magnetic rotor to eliminate complex bearing structures and enable low-friction actuation. Compared to preceding tubular designs, the planar topology allows for 83% downsizing in the actuator’s axial size, which helps preserve probe flexibility. Furthermore, the hollow design provides an unobstructed optical path through the actuator body, which removes imaging blind spots. A proof-of-concept scanner device is prototyped using flex-circuit microfabrication and 3D printing techniques for its electromechanical characterization. The prototype is successfully driven to revolve the rotor with 45° steps on a ring-shaped planar stator, which are then cycled at high frequencies to continuously spin the rotor up to a maximum rate of 2000 rpm with a device temperature below 45 °C, a safety threshold for tissue damage. The demonstrated stepwise and high-speed modes of laser scanning suggests the feasibility of the scanner design for multimodal imaging application toward advancing optical endoscope technology.

Introduction

Endoscopic imaging is becoming a more common way to detect diseases early because it allows physicians to directly observe the hard-to-reach areas inside the body, ranging from the arteries to the esophagus [1], [2], [3], [4]. Optical endoscopes use various imaging techniques, such as white light endoscopy, optical coherence tomography (OCT), Raman spectroscopy, and others [1]. Endoscopic OCT renders high resolution (<3 µm) images of tissue cross-sections in real time [5], while Raman spectroscopy analyzes chemical composition to differentiate between normal and diseased tissues [6], [7]. Both OCT and Raman endoscopic methods direct a laser beam to the area of interest using either a forward- or side-viewing optic fiber probe, and then analyze the reflected light along the same optical path [1], [8]. The forward-viewing configuration sees directly in front of the probe and is useful for performing medical procedures like biopsies; however, scanning the imaging beam is extremely difficult [9]. The side-viewing configuration bends the light 90° with an angled mirror at the distal tip of the probe, which, when continuously revolved for 360°, can image the entire sidewall of a lumen [8].

There have been a wide range of studies on improving image quality in side-viewing probes by using distal optical scanners to reduce the image distortion caused by rotating the entire probe equipped with a fixed distal mirror [4], [8], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]. The distal scanners reported to use small commercial motors are, however, limited in both functionality and cost by scanning at only high speeds, being axially long, and being prohibitively expensive for disposable use ($1000-$2000) [8], [25]. While distal scanners based on micro-electro-mechanical systems (MEMS) have been developed to address some of these issues [26], [27], [28] they have inherent limitations in their scanning range (e.g., ± 20° [26]) due to the 2-dimensional (2D) nature of silicon-based devices. These shortcomings of reported distal scanners pose a barrier for increasing the imaging modalities and capabilities of endoscopes. For example, multimodal imaging is of clinical interest to provide physicians with more information through 360° side-viewing endoscopy, but requires a scanner with a large range of rotational speeds (e.g., precision stepping for Raman Spectroscopy and high speed for OCT) [18].

Micro rotary actuators using ferrofluid bearings have been investigated to address this need, allowing for both stepwise and continuous modes of operation, while reducing the structural design complexity [17], [18], [19], [22], [23]. The working principle of this ferrofluid-assisted actuator is discussed elsewhere [29]. Briefly, ferrofluids are magnetic liquids constructed by suspending ferromagnetic nanoparticles in a carrier fluid, which concentrates in areas with higher magnetic flux density, e.g., the poles of a permanent magnet [30]. The accumulated ferrofluid in these areas can lift the magnet against its substrate, creating a low friction bearing. This principle was used in previous tubular micro actuators to both center and lubricate the rotor without needing micromachined bearings [17], [18], [19], [22], [23]. However, these actuators use rotors with relatively long axial sizes (e.g., 3 mm), which reduces the overall flexibility of the catheter when integrated [18]. Additionally, the electrical wiring of these actuators and others [20] blocks parts of the imaging beam during rotation, resulting in blind spots in a large portion of the visual field [15], [16].

The current work leverages the advantages of the ferrofluid bearing mechanism to study a novel planar micro rotary actuator for its potential application to side-viewing endoscopic probes (Fig. 1(a)). The primary aim of adopting the planar architecture is to drastically reduce the axial length of the actuator, which in turn enhances the flexibility (and thus maneuverability) of the integrated probe. Additionally, the new actuator is designed to have a hollow structure to eliminate the shadowing effects. To achieve the hollow design, a mirror is attached to the distal end of a ring magnetic rotor that is spun by the proximally placed hollow planar stator. This creates an unobstructed optical path through the entire actuator, into the rotating mirror, and out of the scanner. The design and prototyping for the above planar actuator and optical scanner are discussed in the next section. This is followed by the experimental results from the electromechanical characterization of the fabricated prototype, and a demonstration of circumferential laser scanning to verify its viability as an endoscopic optical scanner.

Section snippets

Working principle and design

The overall design of the optical scanner device is illustrated in Fig. 1(b). The actuator is constructed using a ring magnet as the rotor with a single-copper-layered ring stator (similar in construction to previous stator designs [17], [18], [19], [22], [23]) placed in-plane under the magnet. The magnet is polarized along its diametral direction and is aligned to the pole of the rotating magnetic field produced by the planar stator. Ferrofluid is applied to the magnet such that it groups

Micro actuator and scanner

This work uses a ring magnet of neodymium 50 (R0100D-10, SuperMagnetMan, AL, USA) with an outer diameter (OD) of 1 mm, inner diameter (ID) of 0.5 mm, and thickness of 0.5 mm as the rotor. The bearing of the actuator is an oil-based ferrofluid (EFH-1 FerroTec, CA, USA; saturation magnetization 44 mT, viscosity 6 mPa·s). The hollow axle is made using a 304 stainless-steel tube (0.508-mm OD and 0.3-mm ID) whose OD is fine adjusted down to allow for press-fitting into the hole of the ring magnet.

Experimental results

The fabricated ferrofluid-assisted planar rotary actuator was successfully operated in both stepping and high-speed modes as designed. The actuator itself (without the lighthouse and prism mirror) was first experimentally characterized to analyze the electromechanical performances of the actuator (4.1 Stepping actuation, 4.2 High-speed actuation). Optical scanning was then tested using the scanner prototype by passing a laser beam through the actuator and into the mirror to show continuous

Discussion

The actuator’s current draw increased with drive speed because larger torques were necessary to decrease the rotor’s response time [23]. The initial current to start rotation (2.2 A for 100 rpm, Fig. 6) was required to overcome the inherent static friction and inertia in the system. Once the actuator started to spin, it was relatively power efficient (100′s of mA increase in current led to 100 s of rpm increase). This is likely because dynamic friction is typically smaller than the static

Conclusions

This work has investigated a planar and hollow micro rotary actuator enabled by a self-sustained ferrofluid bearing. Electromagnetic simulation was conducted to define the actuator design, which was then prototyped to build a proof-of-concept scanner device. The planar form of the actuator enabled significant reduction in its axial size, and the use of a ferrofluid bearing contributed to further miniaturization. The fabricated device was tested to verify the designed actuation functions.

CRediT authorship contribution statement

Kyle Searles: Methodology, Investigation, Validation, Visualization, Writing - Original Draft, Writing - Review & Editing. Nabil Shalabi: Methodology, Investigation, Validation, Writing - Review & Editing. Sayed Mohammad Hashem Jayhooni: Methodology, Resources, Writing - Review & Editing, Kenichi Takahata: Conceptualization, Methodology, Supervision, Project administration, Funding acquisition, Writing - Review & Editing.

Declaration of Competing Interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Acknowledgments

This work was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC, grant no. I2IPJ556130-20). K. Searles was partially supported by a NSERC scholarship. The authors thank Change Ge and Ryan Yang for their assistance in device prototyping. The authors also thank the Advanced Nanofabrication Facility and the Centre for Electronics and Textiles at the University of British Columbia for providing access to the tools used for stator fabrication and 3D printing.

Kyle Searles received the B.Sc. degree in biomedical engineering from the University of Texas at Dallas, Richardson, TX in 2020. He is currently working towards the M.Sc. degree in biomedical engineering at the University of British Columbia, Vancouver, BC. His research interests include MEMS, ferrofluid based micro actuators, optical endoscopy, capacitive pressure sensors, and inductive coupling of LC-tanks for wireless communication.

References (32)

  • H.-C. Lee et al.

    Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter

    Biomed. Opt. Express

    (2016)
  • T.-H. Tsai et al.

    Endoscopic optical coherence tomography for clinical gastroenterology

    Diagnostics

    (2014)
  • M.J. Gora et al.

    Endoscopic optical coherence tomography: technologies and clinical applications [Invited]

    Biomed. Opt. Express

    (2017)
  • R. Ansari et al.

    All-optical forward-viewing photoacoustic probe for high-resolution 3D endoscopy

    Light Sci. Appl.

    (2018)
  • Z. Pang et al.

    Miniaturized magnetic-driven scanning probe for endoscopic optical coherence tomography

    Biomed. Opt. Express

    (2015)
  • T. Wang et al.

    Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography

    Biomed. Opt. Express

    (2015)
  • Kyle Searles received the B.Sc. degree in biomedical engineering from the University of Texas at Dallas, Richardson, TX in 2020. He is currently working towards the M.Sc. degree in biomedical engineering at the University of British Columbia, Vancouver, BC. His research interests include MEMS, ferrofluid based micro actuators, optical endoscopy, capacitive pressure sensors, and inductive coupling of LC-tanks for wireless communication.

    Nabil Shalabi received a B.Eng. (Honors) from McGill University, Montreal, Canada in Mechanical Engineering (2009), a M.Eng. from McGill in Mechanical Engineering and Microresonators (2011), and a Ph.D. from McGill in Mechanical Engineering and Muscle Biophysics (2017). Since then, he completed a Postdoctoral Associate position at Cornell University, NY, USA on micro/nanotechnologies (2018), a Graduate Science Commercialization Business Certificate from Simon Fraser University, Vancouver, Canada (2020), and is currently a Postdoctoral Fellow at the University of British Columbia, Vancouver, Canada (2018-present). Nabil is an expert in micro/nanodevices and has made MEMS wireless capacitive pressure sensors for kidney stone applications, NEMS RF nano-switches for zero power sensors, and MEMS cantilevers for measuring protein interactions.

    Sayed Mohammad Hashem Jayhooni received the B.Sc. and M.Sc. degrees in Mechanical Engineering from Shiraz University, Shiraz, Iran, in 2010 and 2013, respectively, and received his Ph.D. in Biomedical Engineering at the University of British Columbia, Vancouver, Canada in 2020. He is presently a postdoctoral fellow in the Department of Electrical and Computer Engineering at the University of British Columbia, collaborating with the BC Cancer Research Centre for minimally invasive endoscopic devices. His research interests include biomedical imaging, fiber optics, Raman spectroscopy, optical coherence tomography, ferrofluid-based micro actuators and sensors, implantable microdevices, MEMS, heat transfer and thermofluids mechanics.

    Kenichi Takahata is a Professor in the Department of Electrical and Computer Engineering at the University of British Columbia, Vancouver, Canada. He received the B.S. degree in physics from Sophia University, Tokyo, Japan, in 1990 and the M.S. and Ph.D. degrees in electrical engineering from the University of Michigan, Ann Arbor, in 2004 and 2005, respectively. He joined Matsushita Research Institute Tokyo, Inc. in 1990 and was with Matsushita Electric Industrial Co. (presently Panasonic), Japan, until 2001. He held a Visiting Scientist position at the University of Wisconsin, Madison from 1999 to 2001. He was a Senior Research Engineer in the Corporate Research Laboratory at 3 M Company, St. Paul, USA from 2005 to 2006 prior to joining the University of British Columbia. His research interests are in the areas of microsystems, medical MEMS, nanotechnology, micro/nanomanufacturing, and microplasma control and applications.

    View full text