Editorial
On the horns of a dilemma: choosing total intravenous anaesthesia or volatile anaesthesia

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Summary

There are two established techniques of delivering general anaesthesia: propofol-based total intravenous anaesthesia (TIVA) and volatile agent-based inhaled anaesthesia. Both techniques are offered as standard of care and have an established safety track record lasting more than 30 years. However, it is not currently known whether the choice of anaesthetic technique results in a fundamentally different patient experience or affects early, intermediate-term, and longer-term postoperative outcomes. This editorial comments on a recently published study that suggests that inhaled volatile anaesthesia might be associated with fewer postoperative surgical complications than propofol-based TIVA for patients undergoing colorectal cancer surgery. We consider the strengths and limitations of the study, place these findings in the context of the broader evidence, and discuss how the current controversies regarding anaesthetic technique can be resolved, thereby helping to bring precision medicine into the modern practice of perioperative care.

Keywords

inhalational anaesthesia
postoperative complications
postoperative outcomes
precision medicine
propofol
TIVA
total intravenous anaesthesia
volatile anaesthesia

Cited by (0)

This editorial accompanies: Inhalation anaesthesia compared with total intravenous anaesthesia and postoperative complications in colorectal cancer surgery: an observational registry-based study by Hasselager et al., Br J Anaesth 2022:129:416–426, doi: 10.1016/j.bja.2022.03.019