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IMPLANTED BIOMATERIALS

Sutureless gastrointestinal anastomoses

Nature Biomedical Engineering volume 6, pages 1089–1091 (2022)Cite this article

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An adhesive hydrogel patch made from off-the-shelf materials seals and aids the healing of gastrointestinal-tissue defects without the need for sutures, as shown with the repair of gastrointestinal leaks in live rats and pigs.

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Fig. 1: An adhesive patch for the sutureless sealing of anastomotic gastrointestinal leaks.
Fig. 2: Mechanisms of adhesion, and conditions for the testing of adhesives for the repair of gastrointestinal leaks.

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Authors and Affiliations

  1. Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Zurich, Switzerland

    Alexandre H. C. Anthis & Inge K. Herrmann

  2. Particles-Biology Interactions, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen, Switzerland

    Alexandre H. C. Anthis & Inge K. Herrmann

  3. Department of Visceral Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland

    Andrea A. Schlegel

  4. Center for Preclinical Research, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

    Andrea A. Schlegel

  5. Clinic for Visceral Surgery, Cantonal Hospital Aarau, Aarau, Switzerland

    Mark Hartel

Authors
  1. Alexandre H. C. Anthis
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  2. Andrea A. Schlegel
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  3. Mark Hartel
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  4. Inge K. Herrmann
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Corresponding author

Correspondence to Inge K. Herrmann.

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Competing interests

A.H.C.A. and I.K.H. are inventors on the patent application ‘Kit comprising adhesive hydrogel and impregnating fluid’ (PCT/EP2022/051137). The other authors declare no competing interests.

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Anthis, A.H.C., Schlegel, A.A., Hartel, M. et al. Sutureless gastrointestinal anastomoses. Nat. Biomed. Eng 6, 1089–1091 (2022). https://doi.org/10.1038/s41551-022-00900-7

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