Substance addiction is a major public health crisis. Neuromodulation treatments show promise, but the therapeutic targets remain unclear. Studying human brain lesions that led to addiction remission with the lesion-network-mapping approach resulted in the identification of a brain circuit shared across addiction disorders that may have therapeutic potential.
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References
Volkow, N. D. & Boyle, M. Neuroscience of addiction: relevance to prevention and treatment. Am. J. Psychiatry 175, 729–740 (2018). A review article presenting an overview of addiction circuitry and opportunities and challenges for treatment.
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This is a summary of: Joutsa, J. et al. Brain lesions disrupting addiction map to a common human brain circuit. Nat. Med. https://doi.org/10.1038/s41591-022-01834-y (2022).
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A human brain circuit for addiction remission. Nat Med 28, 1137–1138 (2022). https://doi.org/10.1038/s41591-022-01864-6
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DOI: https://doi.org/10.1038/s41591-022-01864-6
