Elsevier

Analytica Chimica Acta

Volume 1222, 22 August 2022, 340039
Analytica Chimica Acta

Insights of ion mobility spectrometry and its application on food safety and authenticity: A review

https://doi.org/10.1016/j.aca.2022.340039Get rights and content
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open access

Highlights

  • Insights of Ion Mobility Spectrometry (IMS) in food safety and authenticity.

  • Developments of IMS in terms of sensitivity and resolution.

  • Recent advances in collision cross section reproducibility and prediction.

  • Applications of IMS for food safety and authenticity are reviewed.

  • Target, On-site, Imaging, High-throughput, and fingerprinting IMS approaches.

Abstract

Ion mobility spectrometry (IMS) is gaining importance in the field of food safety and authenticity in recent years due to its main potential to overcome the challenges that arise from the complexity of food matrices. For many years, IMS has been used as a stand-alone analytical detector due to its quick response, high sensitivity, and portability, and stand-alone applications in food analysis have been explored in recent years. At the same time, IMS hyphenation to mass spectrometry (MS) techniques, usually combined with liquid or gas chromatography (LC/GC), provides an additional dimension to separate isobaric compounds and thus improves method selectivity. Besides, with such ion mobility – mass spectrometry (IM−MS) methods, background noise decreases, increasing method sensitivity, and it provides complementary information to mass spectra and retention time with the collision cross section (CCS). The development of CCS databases within the food safety field would even permit the identification of compounds in non-targeted approaches. Furthermore, it would increase the confidence of control laboratories when determining a sample as non-compliant. Therefore, the number of applications by IMS on food safety and authenticity has increased remarkably in recent years. This review provides the general insights of IMS with the current state and recent approaches for its performance improvement and a general outlook of its applicability in food safety and authenticity.

Keywords

Ion mobility spectrometry
Food safety
Authenticity
Collision cross section
Fingerprinting
Imaging
On-site
Mass spectrometry

Cited by (0)

Esra te Brinke received her MSc degree in Natural Sciences in 2012 with a graduation project in plant hormone quantification by LC- and GC-MS. After obtaining her PhD in physical organic chemistry she moved in the direction of organic contaminants. She did a postdoc in the field of water purification and she joined Wageningen Food Safety Research in 2020 as a researcher in veterinary drugs, where she improved her knowledge on various analytical procedures and instruments such as SPE, SLE, ELISA, LC-(HR)MS and IMS. She recently moved back to the water purification field to combine her knowledge on analytical chemistry and common organic pollutants with the development of novel water purification membranes.

Ane Arrizabalaga-Larrañaga graduated in Chemistry in 2016 at the University of the Basque Country and got a Master degree in Analytical Chemistry in 2017 at the University of Barcelona. In July 2021, she received her doctoral degree in Analytical chemistry and Environment at the University of Barcelona. She currently works as researcher in food residues at Wageningen Food Safety Research, part of Wageningen University and Research. Her research interest is the development of new analytical strategies based on mass spectrometry techniques for complex sample analysis, in particular, LC-MS, GC-MS, IMS and AIMS and their application in the field of food analysis.

Marco Blokland obtained his M.Sc. degree in analytical sciences in 2002. He worked at the National Institute of Public Health and the Environment as a study director for various projects related to food safety up until 2010. Since 2010 he has worked as a scientist at Wageningen Food Safety Research (WFSR). His research is focused on the detection of food contaminants using different advanced mass spectrometric techniques.