Research Progress in Design, Synthesis and Application of Benzothiazole-Based Fluorescent Probes

doi:10.6023/cjoc201703041

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (9): 2221-2236.DOI: 10.6023/cjoc201703041 Previous Articles Next Articles

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苯并噻唑基荧光探针的设计、合成与应用研究进展

蒋凯^a, 曹梁^a, 郝志峰^b, 陈美燕^a, 程洁銮^a, 李晓^a, 肖萍^a, 陈亮^a, 汪朝阳^a

a 华南师范大学化学与环境学院教育部环境理论化学重点实验室广州 510006;
b 广东工业大学轻工化工学院广州 510006

收稿日期:2017-03-24 修回日期:2017-05-14 发布日期:2017-05-25
通讯作者: 汪朝阳, 郝志峰 E-mail:wangzy@scnu.edu.cn;haozhifeng3377@163.com
基金资助:
广州市科技计划科学研究专项（No.201607010251）、广东省应用型科技研发专项资金（No.2016B090930004）、华南师范大学大创计划（No.20161415）、广东省自然科学基金（No.2014A030313429）及广东省科技计划（No.2017A010103016）资助项目.

Research Progress in Design, Synthesis and Application of Benzothiazole-Based Fluorescent Probes

Jiang Kai^a, Cao Liang^a, Hao Zhifeng^b, Chen Meiyan^a, Cheng Jieluan^a, Li Xiao^a, Xiao Ping^a, Chen Liang^a, Wang Zhaoyang^a

a School of Chemistry and Environment, Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, South China Normal University, Guangzhou 510006;
b School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006

Received:2017-03-24 Revised:2017-05-14 Published:2017-05-25
Contact: 10.6023/cjoc201703041 E-mail:wangzy@scnu.edu.cn;haozhifeng3377@163.com
Supported by:
Project supported by the Guangzhou Science and Technology Project Scientific Special (No. 201607010251), the Applied Science and Technology Research and Development Special Foundation of Guangdong Province (No. 2016B090930004), the Undergraduates Innovation Project of South China Normal University (No. 20161415), the Natural Science Foundation of Guangdong Province (No. 2014A030313429) and the Guangdong Provincial Science and Technology Project (No. 2017A010103016).

Benzothiazole group is of characteristic fluorescence, and each also contains two heteroatoms (N and S). Hence, benzothiazole group is always viewed as fluorophore and recognition moiety in structure of fluorescent probes, playing an essential role on provision of fluorescence signal and binding sites. Recently, utilizing these properties of benzothiazole moiety to design and synthesize better fluorescent probes has gradually become one of focuses in fluorescent detection research. Classifying benzothiazole-based fluorescent probes into four main categories according to different analytes, such as metal cations, anions, sulfur-containing compounds and other species, the design, synthesis, detecting mechanism and relevant application of these probes are reviewed. And their development tendency in the future is prospected.

Key words: benzothiazole, fluorescent probe, design and synthesis, detecting application, progress

Cite this article

Jiang Kai, Cao Liang, Hao Zhifeng, Chen Meiyan, Cheng Jieluan, Li Xiao, Xiao Ping, Chen Liang, Wang Zhaoyang. Research Progress in Design, Synthesis and Application of Benzothiazole-Based Fluorescent Probes[J]. Chin. J. Org. Chem., 2017, 37(9): 2221-2236.

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苯并噻唑基荧光探针的设计、合成与应用研究进展

Research Progress in Design, Synthesis and Application of Benzothiazole-Based Fluorescent Probes

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