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MOLECULAR ENGINEERING

Making it stick

How T-DNAs become incorporated into the host chromosome has been a subject of lively debate for the last quarter century. Kralemann et al. report data revealing the mechanism of genomic capture of the right border and validating the role of DNA polymerase θ in the capture of the left border.

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Fig. 1: Model from Kralemann et al. for the integration of T-DNA at a pre-existing break.

References

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Correspondence to Anne B. Britt.

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Britt, A.B. Making it stick. Nat. Plants 8, 459–460 (2022). https://doi.org/10.1038/s41477-022-01157-3

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