Abstract
The global community is struggling with the highly contagious COVID-19. Returning to \normal life" now poses risks, and the use of appropriate protective measures has become necessary to continue daily life and protect public health. The main protective measures to prevent transmission of COVID-19 are masks, soaps and disinfectants. Because coronavirus is a \lipid-enveloped virus", it is very sensitive to lipid-dissolving chemicals and can therefore be effectively removed by washing hands sufficiently with soap and water. However, using an alcohol-based disinfectant is a more viable option for outdoor use. Alcohol-based disinfectants are inexpensive, immediately effective, easy to use and better tolerated by the skin compared to other disinfectants. WHO recommends disinfectants containing 75% isopropanol or 80% ethanol as highly effective in inactivating the SARS-CoV-2-virus. The current review discusses the role of alcohol-based hand sanitizers (ABHS) in preventing the spread of viruses, their side effects on human health, and suggests the use of alcohol-based sanitizers as potentially effective in combating the current epidemic.
Zusammenfassung
Die Weltgemeinschaft kämpft mit dem hochansteckenden COVID-19. Die Rückkehr zu einem ,,normalen Leben\ birgt nun Risiken, und die Anwendung geeigneter Schutzmaßnahmen ist notwendig geworden, um das tägliche Leben weiterzuführen und die öffentliche Gesundheit zu schützen. Die wichtigsten Schutzmaßnahmen zur Verhinderung der Übertragung von COVID-19 sind Masken, Seifen und Desinfektionsmittel. Da das Coronavirus ein ,,lipidumhülltes Virus\ ist, reagiert es sehr empfindlich auf lipidauflösende Chemikalien und kann daher durch ausreichendes Waschen der Hände mit Wasser und Seife effektiv entfernt werden. Die Verwendung eines Desinfektionsmittels auf Alkoholbasis ist jedoch eine praktikablere Option für den Einsatz im Freien. Desinfektionsmittel auf Alkoholbasis sind preiswert, sofort wirksam, einfach anzuwenden und werden im Vergleich zu anderen Desinfektionsmitteln besser von der Haut vertragen. Die WHO empfiehlt Desinfektionsmitteln mit 75% Isopropanol oder 80% Ethanol als hochwirksam bei der Inaktivierung des SARS-CoV-2-Virus. Die aktuelle Übersichtsarbeit diskutiert die Rolle von alkoholbasierten Händedesinfektionsmitteln bei der Verhinderung der Ausbreitung von Viren, ihre Nebenwirkungen auf die menschliche Gesundheit und schlägt die Verwendung von alkoholbasierten Desinfektionsmitteln als potenziell wirksam bei der Bekämpfung der aktuellen Epidemie vor.
About the authors
Dr. Narendra Kumar Chaudhary is an Assistant Professor of Chemistry, M.M.A.M. Campus, Tribhuvan University, Biratnagar, Nepal. He has completed his PhD in Bio-inorganic chemistry from Tribhuvan University, Nepal. He has also received Nepal Academy of Science and Technology (NAST) Award to carry out Ph. D.’s thesis.
Biswash Guragain is a final year M. Sc. thesis student of M.M.A.M.Campus, Tribhuvan University, Biratnagar, Nepal.
Summi Rai is a final year M. Sc. thesis student of M.M.A.M.Campus, Tribhuvan University, Biratnagar, Nepal.
Nabina Chaudhary is a Medical Student of Dhaka Central International Medical College, Dhaka University, Bangladesh.
Rahul Chaudhary is a Medical Student of Dhaka Central International Medical College, Dhaka University, Bangladesh.
K. M. Sachin recently submitted Ph. D. thesis to School of Chemical Sciences, Central University of Gujarat, Gandhinagar, India. She has 6 years in research and academic experience. She has solution chemistry and thermodynamic chemistry research areas. She has published 13 research articles. She has also received IRES Excellent Paper Special Award.
Dr. Reena Lamichhane-Khadka is an Associate Professor of Saint Mary’s College, Department of Biology, Notre Dame, Indiana, USA. She completed her PhD from New Mexico State University, USA. Her research interests are in understanding the mechanisms of bacterial resistance to antimicrobial agents, bacterial pathogenesis and stress-tolerance, and development of microbio PADs, paper-based analytical devices to detect microbial contaminants in water, food and medicine.
Dr. Ajaya Bhattarai was born in November 1974. After completing his Ph.D. in 2010 and post-doctoral studies at University of Warsaw, Poland funded by European Commission in 2012-2013 and visiting post-doctoral studies at Boston College as Fulbright scholar for 2018-2019, he has since 2017 been an Assistant Professor in Physical Chemistry at Department of Chemistry, M.M.A.M.C.,Tribhuvan University, Biratnagar, Nepal.
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