Data and code availability
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The atomic coordinates and structure factor amplitudes of the ligand-free and ADP-bound forms of ttMutS2488 are available at the protein databank (https://www.rcsb.org) under accession numbers 7VUF and 7VUK, respectively.
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This paper does not report original code.
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Any additional information required to reanalyze the data reported in this paper is available from the lead contact upon request.