Animal Nutrition

Animal Nutrition

Volume 10, September 2022, Pages 156-166
Animal Nutrition

Review Article
Artificial gut and the applications in poultry: A review

https://doi.org/10.1016/j.aninu.2021.12.010Get rights and content
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open access

Abstract

Artificial gut models including both the gastric and intestinal phases have been used in poultry research for decades to predict the digestibility of nutrients, the efficacy of feed enzymes and additives, and caecal fermentation. However, the models used in the past are static and cannot be used to predict interactions between the feed, gut environment and microbiome. It is imperative that a standard artificial gut model for poultry is established, to enable these interactions to be examined without continual reliance on animals. To ensure the validity of an artificial model, it should be validated with in vivo studies. This review describes current practices in the use of artificial guts in research, their importance in poultry nutrition studies and highlights an opportunity to develop a dynamic gut model for poultry to reduce the number of in vivo experiments.

Keywords

Artificial gut
Gastrointestinal tract
In vitro experiment
Poultry
Simulated gut

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Peer review under responsibility of Chinese Association of Animal Science and Veterinary Medicine.