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Tandem Mass Spectrometry for the Analysis of Ginsenosides in a Phytoadaptogene Composition with Antitumor Properties

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Abstract

The results of an analysis for ginsenosides in the Multiphytoadaptogene (MPA) phytoadaptogene composition with antitumor properties by high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS) are presented. Ginsenosides are identified with the use of commercial standards of ginsenosides and some literature data. Ginsenosides Rb1, Rb2, Rc, Rd, Rg1, Rg2, Re, Rf, and Ro are revealed in MPA. The results could be used for the standardization and quality control of phytocomplexes containing triterpenoid glycosides.

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Funding

This work was supported in part by grants from the Commission on Biomedical Innovations and Technologies of the Ministry of Science of the Russian Federation.

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Authors and Affiliations

  1. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478, Moscow, Russia

    I. V. Kazeev, O. A. Bocharova, V. E. Shevchenko, R. V. Karpova, E. V. Bocharov, M. A. Baryshnikova & V. B. Matveev

  2. All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, 117216, Moscow, Russia

    O. P. Sheichenko

  3. Scientific Research Institute of General Pathology and Pathophysiology, 125315, Moscow, Russia

    V. G. Kucheryanu

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  1. I. V. Kazeev
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  2. O. A. Bocharova
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  3. V. E. Shevchenko
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Correspondence to I. V. Kazeev.

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Translated by E. Glushachenkova

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Kazeev, I.V., Bocharova, O.A., Shevchenko, V.E. et al. Tandem Mass Spectrometry for the Analysis of Ginsenosides in a Phytoadaptogene Composition with Antitumor Properties. Theor Found Chem Eng 55, 1246–1257 (2021). https://doi.org/10.1134/S0040579521050225

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