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Assessing the Association of Kawasaki Disease Symptoms and Echocardiographic Findings

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Abstract

Kawasaki disease is an acute systemic vasculitis which can cause cardiac involvement among other symptoms. In this study we aimed to assess the relationship between the echocardiographic findings of Kawasaki disease with the clinical and paraclinical findings of the patients. In this cross-sectional study, the symptoms of 307 Kawasaki patients were registered and the association of the symptoms with paraclinical findings and echocardiographic studies was assessed. 190 (61.9%) of the patients were male and 117 (38.1%) were female. 193 patients (62.9%) did not have any abnormalities in their echocardiography, while others showed coronary artery aneurysms, perivascular brightness, coronary artery dilatation, and trivial Mitral Regurgitation in their echocardiography. A significant inverse relationship was seen with echocardiographic findings and age. Thrombocytosis, conjunctivitis, and oral and/or pharyngeal erythema and/or strawberry tongue were associated with higher rates of echocardiographic abnormalities. Echocardiographic abnormalities are associated with younger age, higher platelets, and the existence of conjunctivitis and oral and/or pharyngeal erythema and/or strawberry tongue.

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Acknowledgements

The authors would like to thank the research and technology deputy of Shiraz University of Medical Sciences for their financial support. The authors have received a financial grant by the code 18866.

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Authors and Affiliations

  1. Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Seyed Hesamedin Nabavizadeh, Soheila Alyasin & Hossein Esmaeilzadeh

  2. Division of Pediatric Cardiology, Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    Nima Mehdizadegan

  3. Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    Mohsen Moeini

  4. Division of Allergy and Clinical Immunology, Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    Hossein Esmaeilzadeh & Aida Askarisarvestani

  5. Department of Pediatrics, Namazee Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    Aida Askarisarvestani

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  1. Seyed Hesamedin Nabavizadeh
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  2. Nima Mehdizadegan
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  3. Mohsen Moeini
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  4. Soheila Alyasin
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  5. Hossein Esmaeilzadeh
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  6. Aida Askarisarvestani
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Correspondence to Aida Askarisarvestani.

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Nabavizadeh, S.H., Mehdizadegan, N., Moeini, M. et al. Assessing the Association of Kawasaki Disease Symptoms and Echocardiographic Findings. Pediatr Cardiol 43, 816–820 (2022). https://doi.org/10.1007/s00246-021-02792-x

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  • DOI: https://doi.org/10.1007/s00246-021-02792-x

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