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Limit of detection comparison on urine gross alpha/beta, H-3, and P-32 analysis between different liquid scintillation counters

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Abstract

As part of the Centers for Disease Control and Prevention’s post-radiological/nuclear incident response mission, we developed rapid bioassay analytical methods to assess possible human exposure to radionuclides and internal contamination. Liquid scintillation counting (LSC) is a valuable analytical tool for the rapid detection and quantification of gross alpha/beta-emitting radionuclides in urine samples. A key characteristic of this type of bioassay method is its detection sensitivity for the priority threat radionuclides. We evaluated the limit of detection of selected LSC instruments to determine which instrument can be used when low-dose measurement is important.

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Acknowledgements

The authors thank David Saunders for his advice during this work and Po-Yung Cheng for the LOD calculations.

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Authors and Affiliations

  1. Inorganic and Radiation Analytical Toxicology Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, MS S110-5, Atlanta, GA, 30341-3717, USA

    Olga Piraner & Robert L. Jones

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  1. Olga Piraner
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  2. Robert L. Jones
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Correspondence to Olga Piraner.

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The authors declare that they have no competing financial interest.

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Piraner, O., Jones, R.L. Limit of detection comparison on urine gross alpha/beta, H-3, and P-32 analysis between different liquid scintillation counters. J Radioanal Nucl Chem 330, 381–384 (2021). https://doi.org/10.1007/s10967-021-07950-2

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  • DOI: https://doi.org/10.1007/s10967-021-07950-2

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