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Titania-Based Adsorbents for Hydrophilic Interaction Liquid Chromatography

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Abstract

Stationary phases based on titania are obtained by the adsorptive attachment of polyethyleneimine followed by crosslinking with 1,4-butanediol diglycidyl ether. The chromatographic properties of the adsorbents are studied using the Tanaka test for hydrophilic stationary phases and on an example of a separation of a model mixture of water-soluble B vitamins. It is shown that varying the amount of reagents at the stage of synthesis of the stationary phase affects the structure of the functional layer and thereby makes it possible to obtain a adsorbent with improved chromatographic characteristics.

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REFERENCES

  1. Alpert, A.J., J. Chromatogr. A, 1990, vol. 499, p. 177.

    Article  CAS  Google Scholar 

  2. Huber, J.F.K., Pawlowska, M., and Markl, P., J. Chromatogr. A, 1990, vol. 500, p. 257.

    Article  CAS  Google Scholar 

  3. Chernobrovkina, A.V., Smolenkov, A.D., and Shpigun, O.A., Lab. Proizvod., 2018, no. 4, p. 76.

  4. Bather, J.M. and Gray, R.A., J. Chromatogr. A, 1978, vol. 156, p. 21.

    Article  CAS  Google Scholar 

  5. Jaffrezic-Renault, N., Poirier-Andrade, H., and Trang, D.H., J. Chromatogr. A, 1980, vol. 201, p. 187.

    Article  CAS  Google Scholar 

  6. Kawahara, C., Kozbur, X., Gould, S., and Parker, L., Anal. Biochem., 1980, vol. 102, p. 310.

    Article  CAS  Google Scholar 

  7. Kawahara, M., Nakamura, H., and Nakajima, T., J. Chromatogr. A, 1990, vol. 515, p. 149.

    Article  CAS  Google Scholar 

  8. Grun, M., Kurganov, A.A., Schacht, S., Schuth, F., and Unger, K.K., J. Chromatogr. A, 1996, vol. 740, p. 1.

    Article  Google Scholar 

  9. Tani, K. and Suzuki, Y., Chromatographia, 1997, vol. 46, p. 623.

    Article  CAS  Google Scholar 

  10. Tani, K. and Kubojima, H., Chromatographia, 1998, vol. 47, p. 655.

    Article  CAS  Google Scholar 

  11. Tani, K. and Ozawa, M., J. Liq. Chromatogr. Relat. Technol., 1999, vol. 22, p. 843.

    Article  CAS  Google Scholar 

  12. Tani, K., Sumizawa, T., Watanabe, M., Tachibana, M., Koizumi, H., and Kiba, T., Chromatographia, 2002, vol. 55, p. 33.

    Article  CAS  Google Scholar 

  13. Pinkse, M.W., Uitto, P.M., Hilhorst, M.J., Ooms, B., and Heck, A.J., Anal. Chem., 2004, vol. 76, p. 3935.

    Article  CAS  Google Scholar 

  14. Ting, Z. and Lucy, C.A., J. Chromatogr. A, 2008, vol. 1187, p. 87.

    Article  Google Scholar 

  15. Ting, Z. and Lucy, C.A., J. Chromatogr. A, 2010, vol. 1217, p. 82.

    Article  Google Scholar 

  16. Ozawa, M., Tani, K., Nomura, A., Tachibana, M., Koizumi, H., and Kiba, N., Chromatographia, 2009, vol. 70, p. 533.

    Article  CAS  Google Scholar 

  17. Ozawa, M., Tani, K., Tachibana, M., Koizumi, H., and Kiba, N., Chromatographia, 2010, vol. 72, p. 313.

    Article  CAS  Google Scholar 

  18. Moliner-Martinez, Y., Herráez-Hernández, R., Molins-Legua, C., and Campins-Falco, P., J. Chromatogr. A, 2010, vol. 1217, p. 4682.

    Article  CAS  Google Scholar 

  19. Tan, J., Li, R., and Jiang, Z.T., Anal. Methods, 2011, vol. 3, p. 1568.

    Article  CAS  Google Scholar 

  20. Abi, J.M. and Randon, J., J. Chromatogr. A, 2011, vol. 1218, p. 721.

    Article  Google Scholar 

  21. Chicz, R.M., Shi, Z., and Regnier, F.E., J. Chromatogr. A, 1986, vol. 359, p. 121.

    Article  CAS  Google Scholar 

  22. Alpert, A.J. and Regnier, F.E., J. Chromatogr. A, 1979, vol. 185, p. 375.

    Article  CAS  Google Scholar 

  23. Segro, S.S., Cabezas, Y., and Malik, A., J. Chromatogr. A, 2009, vol. 1216, p. 4329.

    Article  CAS  Google Scholar 

  24. Kawachi, Y., Ikegami, T., Takubo, H., Ikegami, Y., Miyamoto, M., and Tanaka, N., J. Chromatogr. A, 2011, vol. 1218, p. 5903.

    Article  CAS  Google Scholar 

  25. Dolci, M., Chromatographic Characterization of Stationary Phases for Hydrophilic Interaction Liquid Chromatography, Cheshire, UK: Thermo Fisher Scientific, 2013.

    Google Scholar 

  26. Buszewski, B. and Noga, S., Anal. Bioanal. Chem., 2012, vol. 402, p. 231.

    Article  CAS  Google Scholar 

  27. Kip, C., Tosun, R.B., Alpaslan, S., Koçer, I., Çelik, E., and Tuncel, A., Talanta, 2019, vol. 200, p. 100.

    Article  CAS  Google Scholar 

  28. Kavathekar, R.S. English, N.J., and Mac-Elroy, J.M.D., Chem. Phys. Lett., 2012, vol. 554, p. 102.

    Article  CAS  Google Scholar 

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Funding

This work was supported by M.V.Lomonosov Moscow State University Program of Development and by the Russian Foundation for Basic Research, project no. 20-03-00909.

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Authors and Affiliations

  1. Department of Chemistry, Moscow State University, 119991, Moscow, Russia

    A. S. Popov, E. A. Tsarenko & A. V. Chernobrovkina

Authors
  1. A. S. Popov
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  2. E. A. Tsarenko
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  3. A. V. Chernobrovkina
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Corresponding author

Correspondence to A. V. Chernobrovkina.

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Translated by V. Kudrinskaya

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Popov, A.S., Tsarenko, E.A. & Chernobrovkina, A.V. Titania-Based Adsorbents for Hydrophilic Interaction Liquid Chromatography. J Anal Chem 76, 1153–1162 (2021). https://doi.org/10.1134/S1061934821100087

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  • DOI: https://doi.org/10.1134/S1061934821100087

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