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IMMUNOMETABOLISM

The IRX(3)some factor in macrophages

Qiu and colleagues identify IRX3 as a driver of macrophage inflammatory cytokines, which can promote metabolic dysfunction.

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Fig. 1: The role of IRX3 in macrophages and the effect of IRX3 on metabolic homeostasis.

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Correspondence to Andrew E. Hogan.

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Moynagh, P.N., Hogan, A.E. The IRX(3)some factor in macrophages. Nat Immunol 22, 1203–1204 (2021). https://doi.org/10.1038/s41590-021-01032-x

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