The marine derived fungus Alternaria alternata (Fr.) Keissl. was isolated from branch samples of Beibu Gulf, Qinzhou, Guangxi, China and identified by 16s rDNA. Chemical study of A. alternata led to the isolation of a new isomer compound named tricycloalternarene 18c and nine known compounds, including alternariol monomethyl ether, mannitol, cyclo(Gly-Ala), tenuazonic acid, allantoin, thymine, uracil, erythritol, and ergosterol. Their chemical structures were identified by extensive spectrum (IR, MS, 1D, and 2D NMR spectra) and compared with the reported literature data.
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ACKNOWLEDGMENT
This research was funded by the Science and Technology Development Project of Guangxi, China (AB16380071), the Guangxi First-class Discipline Project for Pharmaceutical Sciences (GXFCDP-PS-2018), and the Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynthesis Chemistry (GXMNP2018002).
Siyuan Liu and Meiqiong Liu contributed equally to this work.
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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2021, pp. 724–726.
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Liu, S., Liu, M., Wu, H. et al. A New Isomer and Other Metabolites Isolated from Alternaria alternata. Chem Nat Compd 57, 844–847 (2021). https://doi.org/10.1007/s10600-021-03495-8
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DOI: https://doi.org/10.1007/s10600-021-03495-8