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Clinical application of a three-dimensional reconstruction technique for complex liver cancer resection

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Abstract

Objective

To explore the utility of three-dimensional (3D) visualization technology in liver resection for patients with complex liver cancer.

Methods

In this retrospective cohort study, we collected and analyzed clinic pathological data from 105 patients who underwent complicated liver cancer resection at the authors’ unit between January 2014 and June 2019. Observation indicators included general demographic information, operative time, intraoperative blood loss, blood transfusion volume, postoperative liver function, complication rate, hospital stay, and in-hospital mortality.

Results

Compared with the complex liver cancer control group, operative time (257.1  ±  63.4 min versus [vs] 326.6  ±  78.3 min; P < 0.001), intraoperative blood loss (256.4  ±  159.1 mL vs 436.1  ±  177.3 mL; P < 0.001), blood transfusion volume (213.3  ±  185.2 mL vs 401.6  ±  211.2 mL; P < 0.001), and length of hospital stay (9.7  ±  3.1 days vs 11.9  ±  3.3 days; P = 0.001) were significantly reduced in the complex liver cancer reconstruction group. Although there was no statistical difference in total postoperative complication rate between the two groups, the incidence of serious postoperative complications in the reconstruction group was significantly lower than that in the control group (3/54 [5.6%] vs 10/51 [19.6%], respectively; P = 0.038). Regarding laboratory investigations, the time to recovery of liver function in the complex liver cancer reconstruction group was shorter than that in the complex liver cancer control group.

Conclusion

The use of 3D visualization technology was highly influential in formulating meticulous, individualized surgical strategies for complex liver cancer liver resection with safety and reduced perioperative risk.

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Acknowledgements

The authors would like to express our gratitude to Prof. Shao Jianghua from Department of General Surgery, Second Affiliated Hospital of Nanchang University, for his assistance and participation in the conclusion part of this paper. We also thank the Imaging Center of Second Affiliated Hospital of Nanchang University for their superb technical and equipment assistance in data collection and analysis.

Funding

This study was supported by the National Natural Science Foundation of China (81760435) and youth science foundation of Jiangxi (20192ACBL21036).

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Authors and Affiliations

  1. Department of General Surgery, Second Affiliated Hospital of Nanchang University, No. 1, Minde Road, Nanchangm, 330006, China

    Weiwei Sheng, Chendong Yuan, Linquan Wu, Jinlong Yan, Jin Ge & Jun Lei

  2. Jiangxi Province Engineering Research Center of Hepatobiliary Disease, Nanchang, China

    Linquan Wu, Jinlong Yan & Jun Lei

Authors
  1. Weiwei Sheng
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  2. Chendong Yuan
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  3. Linquan Wu
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  4. Jinlong Yan
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  5. Jin Ge
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  6. Jun Lei
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Contributions

Conceptualization: WS, CY, JL. Data analysis: WS, CY, JL. Supply of materials: WS, CY, LW, JY, JG, JL. Draft writing: WS, JL. Final version decision: JL.

Corresponding author

Correspondence to Jun Lei.

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Disclosures

Drs Weiwei Sheng, Chendong Yuan, Linquan Wu, Jinlong Yan, Jin Ge, and Jun Lei have no conflicts of interest or financial ties to disclose.

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Sheng, W., Yuan, C., Wu, L. et al. Clinical application of a three-dimensional reconstruction technique for complex liver cancer resection. Surg Endosc 36, 3246–3253 (2022). https://doi.org/10.1007/s00464-021-08636-2

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  • DOI: https://doi.org/10.1007/s00464-021-08636-2

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