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Radical Functionalization of Geminal Difluoroalkenes

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Abstract

Geminal difluoroalkenes are readily available building blocks for the synthesis of a broad spectrum of organofluorine compounds. The review summarizes published data on radical reactions involving geminal difluoroalkenes. These processes include addition of a radical species to a double bond or one-electron reduction of the difluoroalkene fragment. Particular emphasis has been placed on photocatalytic reactions initiated by visible light.

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Funding

This study was performed under financial support by the Russian Science Foundation (project no. 19-73-00088).

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Authors and Affiliations

  1. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991, Moscow, Russia

    M. O. Zubkov, M. D. Kosobokov & A. D. Dilman

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  1. M. O. Zubkov
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  2. M. D. Kosobokov
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  3. A. D. Dilman
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Correspondence to A. D. Dilman.

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Translated from Zhurnal Organicheskoi Khimii, 2021, Vol. 57, No. 7, pp. 907–928 https://doi.org/10.31857/S0514749221070016.

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Zubkov, M.O., Kosobokov, M.D. & Dilman, A.D. Radical Functionalization of Geminal Difluoroalkenes. Russ J Org Chem 57, 1017–1035 (2021). https://doi.org/10.1134/S1070428021070010

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