Animal Nutrition

Animal Nutrition

Volume 7, Issue 3, September 2021, Pages 823-828
Animal Nutrition

Review Article
Reactive oxygen and nitrogen species regulate porcine embryo development during pre-implantation period: A mini-review

https://doi.org/10.1016/j.aninu.2021.03.007Get rights and content
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open access

Abstract

Significant porcine embryonic loss occurs during conceptus morphological elongation and attachment from d 10 to 20 of pregnancy, which directly decreases the reproductive efficiency of sows. A successful establishment of pregnancy mainly depends on the endometrium receptivity, embryo quality, and utero-placental microenvironment, which requires complex cross-talk between the conceptus and uterus. The understanding of the molecular mechanism regulating the uterine-conceptus communication during porcine conceptus elongation and attachment has developed in the past decades. Reactive oxygen and nitrogen species, which are intracellular reactive metabolites that regulate cell fate decisions and alter their biological functions, have recently reportedly been involved in porcine conceptus elongation and attachment. This mini-review will mainly focus on the recent researches about the role of reactive oxygen and nitrogen species in regulating porcine embryo development during the pre-implantation period.

Keywords

Reactive oxygen and nitrogen species
Pre-implantation
Porcine
Embryo development

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Peer review under responsibility of Chinese Association of Animal Science and Veterinary Medicine.