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Reperfusion therapy in a patient with early recurrence of ischemic stroke

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Abstract

Background

Acute ischemic stroke (AIS) has a high risk of recurrence, particularly in the early stage. Recurrent ischemic stroke (RIS) is associated with adverse neurological outcomes but the phenomenon of early RIS in the endovascular thrombectomy era has not been frequently discussed. We report a case addressing this issue.

Case presentation

We present a patient who was successfully treated by mechanical thrombectomy (MT) for middle cerebral artery occlusion. Due to an early stroke recurrence, within 72 h after the first MT, he received systemic thrombolysis and repeated MT was performed with excellent clinical outcome.

Discussion

We discuss the aspects of reperfusion therapy for patients experiencing early stroke recurrence. Consideration was given to stroke etiology and off-label use of thrombolytic therapy. Also, effectiveness of repeated MT for early re-occlusion of initially reanalyzed vessel was evaluated in order to allow more patients with RIS to benefit from reperfusion therapy.

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Authors and Affiliations

  1. Department of Neurology, Clinical Hospital Centre Rijeka, Kresimirova 42, 51 000, Rijeka, Croatia

    Marina Bralic, Matija Sosic & Vladimira Vuletic

  2. Department of Radiology, Clinical Hospital Centre Rijeka, Rijeka, Croatia

    Slavica Kovacic

Authors
  1. Marina Bralic
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  2. Matija Sosic
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  3. Slavica Kovacic
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  4. Vladimira Vuletic
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Contributions

MB and MS clinical data collection; MB drafted the manuscript; SK contributed to the radiological processing and analysis; VV was in charge of the overall direction and planning. All authors participated in the case design, manuscript revision, and approval of the final version of the manuscript.

Corresponding author

Correspondence to Marina Bralic.

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Conflict of interest

The authors declare no competing interests.

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IRB approval was obtained.

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Obtained.

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Bralic, M., Sosic, M., Kovacic, S. et al. Reperfusion therapy in a patient with early recurrence of ischemic stroke. Neurol Sci 43, 673–676 (2022). https://doi.org/10.1007/s10072-021-05587-3

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  • DOI: https://doi.org/10.1007/s10072-021-05587-3

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