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Prevalence, correlates, and impact of sleep disturbance in Chinese meningioma patients

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Abstract

Purpose

Sleep disturbance is common in meningioma patients and may lead to disease aggravation and decreases health-related quality of life (HRQoL). However, the sleep quality of meningioma patients newly diagnosed and ready for surgery has not been well clarified in China. This study aims to evaluate the prevalence, correlates, and impact of sleep disturbance among Chinese meningioma patients.

Methods

In this cross-sectional study, meningioma patients were recruited from the Affiliated Hospital of Nantong University from January 2020 to November 2020. A series of questionnaires were applied: the 0–10 Numerical Rating Scale (NRS), the Hospital Anxiety and Depression Scale (HADS), the Multidimensional Fatigue Inventory (MFI-20), the Epworth Sleepiness Scale (ESS), the Short-Form 36 (SF-36), the Pittsburgh Sleep Quality Index (PSQI). Independent samples t test, Mann–Whitney U test, chi-square analysis, Pearson/Spearman correlation, and binary logistic regression were used to analyze the data.

Results

One hundred meningioma patients completed the questionnaires. Sleep disturbance affected 43% of the meningioma patients and was linked to many concomitant symptoms, such as headache, fatigue, anxiety, and depression. Binary logistic regression indicated that fatigue and headache were independently associated with sleep disturbance of meningioma patients. Meanwhile, severe sleep disturbance led to lower quality of life.

Conclusions

These findings demonstrated that a considerable number of meningioma patients newly diagnosed and ready for surgery suffered from sleep disturbance, potentially contributing to impair HRQoL. Medical personnel should pay more attention to meningioma patients with sleep disturbance and take effective measures to improve sleep quality, with the ultimate goal to improve their HRQoL.

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Data availability

All data generated or analyzed during this study are available upon reasonable request to the corresponding author.

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Acknowledgements

The authors are thankful to Zhifeng Gu, Liren Li, and Chen Dong for their assistance with this paper as well as all patients who participated in the study.

Funding

This study was supported by Science and technology Project of Nantong City, Grant Number: MS12020011, Clinical Research Center of Stem Cells, Affiliated Hospital of Nantong University, Nantong: HS2018001, Science and technology Project of Jiangsu Province, Grant/Award Number: BE2018671 and Postgraduate Research & Practice Innovation Program of Jiangsu Province, Grant/Award Number: KYCX21_3106.

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Author notes

  1. Dandan Zhang, Jing Wang, and Xixi Gu contributed equally to this work

Authors and Affiliations

  1. Department of Nursing, Affiliated Hospital of Nantong University, Nantong University, 20th Xisi Road, Nantong, 226001, China

    Dandan Zhang, Xixi Gu & Chen Dong

  2. Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong University, 20th Xisi Road, Nantong, 226001, China

    Dandan Zhang & Xiaomei Zhang

  3. Department of Medical Image, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, China

    Jing Wang

  4. Department of Rheumatology, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, China

    Zhifeng Gu & Chen Dong

  5. Department of Gastroenterology, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, China

    Liren Li

  6. Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, China

    Rui Zhao

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  1. Dandan Zhang
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  2. Jing Wang
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  3. Xixi Gu
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  4. Zhifeng Gu
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  5. Liren Li
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  6. Chen Dong
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  7. Rui Zhao
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  8. Xiaomei Zhang
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Corresponding authors

Correspondence to Rui Zhao or Xiaomei Zhang.

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This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of the Affiliated Hospital of Nantong University (No. 2020-K042).

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Zhang, D., Wang, J., Gu, X. et al. Prevalence, correlates, and impact of sleep disturbance in Chinese meningioma patients. Support Care Cancer 30, 1231–1241 (2022). https://doi.org/10.1007/s00520-021-06504-2

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