Abstract
The presence of intraventricular hemorrhage (IVH) portends a worse prognosis in patients presenting with spontaneous intracerebral hemorrhage (ICH). Intraventricular hemorrhage increases the rates of hydrocephalus, ventriculitis, and long-term shunt dependence. Over the past decade, novel medical devices and protocols have emerged to directly treat IVH. Presently, we review new technological adaptations to treating intraventricular hemorrhage in an effort to focus further innovation in treating this morbid neurosurgical pathology. We summarize current and historical treatments as well as innovations in IVH including novel procedural techniques, use of the Integra Surgiscope, use of the Artemis evacuator, use of BrainPath, novel catheter technology, large bore external ventricular drains, the IRRAflow, the CerebroFlo, and the future directions of the field. Technology and medical devices for both surgical and nonsurgical methods are advancing the treatment of IVH. With many promising new technologies on the horizon, prospects for improved clinical care for IVH and its etiologies remain hopeful.
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References
Abunimer AM, Abou-Al-Shaar H, Cavallo C, Mahan MA, Labib MA (2018) Minimally invasive approaches for the management of intraventricular hemorrhage. J Neurosurg Sci 62(6):734–744
Alan N, Lee P, Ozpinar A, Gross BA, Jankowitz BT (2017) Robotic stereotactic assistance (ROSA) utilization for minimally invasive placement of intraparenchymal hematoma and intraventricular catheters. World Neurosurg 108:996.e7-e10. https://doi.org/10.1016/j.wneu.2017.09.027
Alexopoulos G, Prim M, Khan M, Quadri N, Urquiaga JF, El Tecle N et al (2020) Minimally invasive evacuation of severe intraventricular hemorrhage using the BrainPath endoport-assisted microsurgical system. World Neurosurg 134:e540–e548. https://doi.org/10.1016/j.wneu.2019.10.135
Aten Q, Killeffer J, Seaver C, Reier L (2020) Causes, complications, and costs associated with external ventricular drainage catheter obstruction. World Neurosurg 134:501–506. https://doi.org/10.1016/j.wneu.2019.10.105
Atzema C, Mower WR, Hoffman JR, Holmes JF, Killian AJ, Wolfson AB (2006) Prevalence and prognosis of traumatic intraventricular hemorrhage in patients with blunt head trauma. J Trauma 60(5):1010–1017. https://doi.org/10.1097/01.ta.0000218038.28064.9d
Aucoin PJ, Kotilainen HR, Gantz NM, Davidson R, Kellogg P, Stone B (1986) Intracranial pressure monitors. Epidemiologic study of risk factors and infections. Am J Med 80(3):369–376. https://doi.org/10.1016/0002-9343(86)90708-4
Awad IA, Polster SP, Carrión-Penagos J, Thompson RE, Cao Y, Stadnik A et al (2019) Surgical performance determines functional outcome benefit in the minimally invasive surgery plus recombinant tissue plasminogen activator for intracerebral hemorrhage evacuation (MISTIE) procedure. Neurosurgery 84(6):1157–1168. https://doi.org/10.1093/neuros/nyz077
Bander ED, Jones SH, Kovanlikaya I, Schwartz TH (2016) Utility of tubular retractors to minimize surgical brain injury in the removal of deep intraparenchymal lesions: a quantitative analysis of FLAIR hyperintensity and apparent diffusion coefficient maps. J Neurosurg 124(4):1053–1060
Broderick JP, Berkhemer OA, Palesch YY, Dippel DW, Foster LD, Roos YB et al (2015) Endovascular therapy is effective and safe for patients with severe ischemic stroke: pooled analysis of interventional management of stroke III and multicenter randomized clinical trial of endovascular therapy for acute ischemic stroke in the Netherlands data. Stroke 46(12):3416–3422. https://doi.org/10.1161/STROKEAHA.115.011397
Brouwers PJ, Dippel DW, Vermeulen M, Lindsay KW, Hasan D, van Gijn J (1993) Amount of blood on computed tomography as an independent predictor after aneurysm rupture. Stroke 24(6):809–814. https://doi.org/10.1161/01.str.24.6.809
Carney N, Totten AM, O’Reilly C, Ullman JS, Hawryluk GW, Bell MJ et al (2017) Guidelines for the management of severe traumatic brain injury Fourth Edition. Neurosurgery 80(1):6–15. https://doi.org/10.1227/NEU.0000000000001432
Carpenter AM, Singh IP, Gandhi CD, Prestigiacomo CJ (2016) Genetic risk factors for spontaneous intracerebral haemorrhage. Nat Rev Neurol 12(1):40–49. https://doi.org/10.1038/nrneurol.2015.226
Cavallo C, Zhao X, Abou-Al-Shaar H, Weiss M, Gandhi S, Belykh E et al (2018) Minimally invasive approaches for the evacuation of intracerebral hemorrhage: a systematic review. J Neurosurg Sci 62(6):718–733. https://doi.org/10.23736/S0390-5616.18.04557-5
Chau CYC, Craven CL, Rubiano AM, Adams H, Tülü S, Czosnyka M et al (2019) The evolution of the role of external ventricular drainage in traumatic brain injury. J Clin Med. https://doi.org/10.3390/jcm8091422
Coulson NK, Chiarelli PA, Su DK, Chang JJ, MacConaghy B, Murthy R et al (2015) Ultrasound stylet for non-image-guided ventricular catheterization. J Neurosurg Pediatr 16(4):393–401. https://doi.org/10.3171/2015.2.PEDS14387
de Havenon A, Joyce E, Yaghi S, Ansari S, Delic A, Taussky P et al (2020) End-of-treatment intracerebral and ventricular hemorrhage volume predicts outcome: a secondary analysis of MISTIE III. Stroke 51(2):652–654. https://doi.org/10.1161/STROKEAHA.119.028199
Di Rienzo A, Colasanti R, Esposito D, Della Costanza M, Carrassi E, Capece M et al (2020) Endoscope-assisted microsurgical evacuation versus external ventricular drainage for the treatment of cast intraventricular hemorrhage: results of a comparative series. Neurosurg Rev 43(2):695–708. https://doi.org/10.1007/s10143-019-01110-7
Dimitriou J, Levivier M, Gugliotta M (2016) Comparison of complications in patients receiving different types of intracranial pressure monitoring: a retrospective study in a single center in Switzerland. World Neurosurg 89:641–646. https://doi.org/10.1016/j.wneu.2015.11.037
Dorresteijn K, Brouwer MC, Jellema K, van de Beek D (2020) Bacterial external ventricular catheter-associated infection. Expert Rev Anti-infect Ther 18(3):219–229. https://doi.org/10.1080/14787210.2020.1717949
Du B, Shan AJ, Peng YP, Wang J, Peng KW, Zhong XL et al (2018) A new modified neuroendoscope technology to remove severe intraventricular haematoma. Brain Inj 32(9):1142–1148. https://doi.org/10.1080/02699052.2018.1469042
Echeverry N, Mansour S, MacKinnon G, Jaraki J, Shapiro S, Snelling B (2020) Intracranial tubular retractor systems: a comparison and review of the literature of the BrainPath, Vycor, and METRx tubular retractors in the management of deep brain lesions. World Neurosurg 143:134–146
Fahim DK, Relyea K, Nayar VV, Fox BD, Whitehead WE, Curry DJ, Luerssen TG, Jea A (2009) Transtubular microendoscopic approach for resection of a choroidal ateriovenous malformation. J Neurosurg Pediatr 3(2):101–104
Fargen KM, Hoh BL, Neal D, O’Connor T, Rivera-Zengotita M, Murad GJ (2016) The burden and risk factors of ventriculostomy occlusion in a high-volume cerebrovascular practice: results of an ongoing prospective database. J Neurosurg 124(6):1805–1812. https://doi.org/10.3171/2015.5.JNS15299
Fernandes HM, Gregson B, Siddique S, Mendelow AD (2000) Surgery in intracerebral haemorrhage. The uncertainty continues. Stroke 31(10):2511–2516. https://doi.org/10.1161/01.str.31.10.2511
Findlay JM, Choi DW, Grotta JC, Weird B, Wolf PA, Mohr JP (2004) Stroke: pathophysiology, diagnosis, management. Elsevier, New York
Fiorella D, Arthur A, Bain M, Mocco J (2016) Minimally invasive surgery for intracerebral and intraventricular hemorrhage: rationale, review of existing data and emerging technologies. Stroke 47(5):1399–1406. https://doi.org/10.1161/STROKEAHA.115.011415
Fried HI, Nathan BR, Rowe AS, Zabramski JM, Andaluz N, Bhimraj A et al (2016) The insertion and management of external ventricular drains: an evidence-based consensus statement: a statement for healthcare professionals from the Neurocritical Care Society. Neurocrit Care 24(1):61–81. https://doi.org/10.1007/s12028-015-0224-8
Gaberel T, Magheru C, Parienti JJ, Huttner HB, Vivien D, Emery E (2011) Intraventricular fibrinolysis versus external ventricular drainage alone in intraventricular hemorrhage: a meta-analysis. Stroke 42(10):2776–2781. https://doi.org/10.1161/STROKEAHA.111.615724
Garegnani L, Va Franco J, Ciapponi A, Garrote V, Vietto V, Portillo Medina SA (2020) Ventriculo-peritoneal shunting devices for hydrocephalus. Cochrane Database Syst Rev 6(6):CD012726
Gilard V, Djoubairou BO, Lepetit A, Metayer T, Gakuba C, Gourio C et al (2017) Small versus large catheters for ventriculostomy in the management of intraventricular hemorrhage. World Neurosurg 97:117–122. https://doi.org/10.1016/j.wneu.2016.09.105
Gonen L, Chakravarthi SS, Monroy-Sosa A, Celix JM, Kojis N, Singh M et al (2017) Initial experience with a robotically operated video optical telescopic-microscope in cranial neurosurgery: feasibility, safety, and clinical applications. Neurosurg Focus 42(5):E9. https://doi.org/10.3171/2017.3.FOCUS1712
Goyal N, Tsivgoulis G, Malhotra K, Katsanos AH, Pandhi A, Alsherbini KA et al (2019) Minimally invasive endoscopic hematoma evacuation vs best medical management for spontaneous basal-ganglia intracerebral hemorrhage. J Neurointerv Surg 11(6):579–583. https://doi.org/10.1136/neurintsurg-2018-014447
Graeb DA, Robertson WD, Lapointe JS, Nugent RA, Harrison PB (1982) Computed tomographic diagnosis of intraventricular haemorrhage. Etiology and prognosis. Radiology 143(1):91–96. https://doi.org/10.1148/radiology.143.1.6977795
Greenfield JP, Cobb WS, Tsouris AJ, Schwartz TH (2008) Stereotactic minimally invasive tubular retractor system for deep brain lesions. Neurosurgery 63(4 Suppl 2):334–339
Hanley DF, Lane K, McBee N, Ziai W, Tuhrim S, Lees KR et al (2017) Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial. Lancet 389(10069):603–611. https://doi.org/10.1016/S0140-6736(16)32410-2
Hanley DF, Naff NJ, Harris DM (2005) Intraventricular hemorrhage: presentation and management options. Semin Cerebrovasc Dis Stroke 5(3):209–216. https://doi.org/10.1053/j.scds.2006.01.011
Hanley DF, Thompson RE, Rosenblum M, Yenokyan G, Lane K, McBee N et al (2019) Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. Lancet (Lond Engl). 393(10175):1021–1032. https://doi.org/10.1016/S0140-6736(19)30195-3
Harbaugh RE, Coudwell W, Berger M (2015) Neurosurgery knowledge update: a comprehensive review. Thieme Medical Publishers, New York
Hauptman JS, Lutz BR, Hanak BW, Browd SR (2018) Technical advances in the treatment of hydrocephalus: current and future state. In: Cerebrospinal fluid disorders. Springer, Cham, pp 363–380
Hersh EH, Gologorsky Y, Chartrain AG, Mocco J, Kellner CP (2018) Minimally invasive surgery for intracerebral hemorrhage. Curr Neurol Neurosci Rep 18(6):34. https://doi.org/10.1007/s11910-018-0836-4
Hu WJ, Eaton JW, Ugarova TP, Tang L (2001) Molecular basis of biomaterial-mediated foreign body reactions. Blood 98(4):1231–1238. https://doi.org/10.1182/blood.v98.4.1231
Jabbarli R, Reinhard M, Roelz R, Shah M, Neisen WD, Kaier K, Taschner C, Weyerbrock A, Van Velthoven V (2016) The predictors and clinical impact of intraventricular hemorrhage in patients with aneurysmal subarachnoid hemorrhage. Int J Stroke 11(1):68–76
Juvela S, Siironen J, Kuhmonen J (2005) Hyperglycemia, excess weight, and history of hypertension as risk factors for poor outcome and cerebral infarction after aneurysmal subarachnoid hemorrhage. J Neurosurg 102(6):998–1003. https://doi.org/10.3171/jns.2005.102.6.0998
Kellner CP, Chartrain AG, Nistal DA, Scaggiante J, Hom D, Ghatan S et al (2018) The Stereotactic Intracerebral Hemorrhage Underwater Blood Aspiration (SCUBA) technique for minimally invasive endoscopic intracerebral hemorrhage evacuation. J Neurointerv Surg 10(8):771–776. https://doi.org/10.1136/neurintsurg-2017-013719
Konstantelias AA, Vardakas KZ, Polyzos KA, Tansarli GS, Falagas ME (2015) Antimicrobial-impregnated and -coated shunt catheters for prevention of infections in patients with hydrocephalus: a systematic review and meta-analysis. J Neurosurg 122(5):1096–1112. https://doi.org/10.3171/2014.12.JNS14908
Kramer AH, Mikolaenko I, Deis N, Dumont AS, Kassell NF, Bleck TP et al (2010) Intraventricular hemorrhage volume predicts poor outcomes but not delayed ischemic neurological deficits among patients with ruptured cerebral aneurysms. Neurosurgery 67(4):1044–1052. https://doi.org/10.1227/NEU.0b013e3181ed1379
Kuo LT, Lu HY, Tsai JC, Tu YK (2018) Prediction of shunt dependency after intracerebral hemorrhage and intraventricular hemorrhage. Neurocrit Care 29(2):233–240. https://doi.org/10.1007/s12028-018-0532-x
Lang SS, Zhang B, Yver H, Palma J, Kirschen MP, Topjian AA et al (2019) Reduction of ventriculostomy-associated CSF infection with antibiotic-impregnated catheters in pediatric patients: a single-institution study. Neurosurg Focus 47(2):E4. https://doi.org/10.3171/2019.5.FOCUS19279
Lozier AP, Sciacca RR, Romagnoli MF, Connolly ES Jr (2002) Ventriculostomy-related infections: a critical review of the literature. Neurosurgery 51(1):170–181. https://doi.org/10.1097/00006123-200207000-00024
Marenco-Hillembrand L, Prevatt C, Suarez-Meade P, Ruiz-Garcia H, Quinones- Hinojosa A, Chaichana KL (2020) Minimally invasive surgical outcomes for deep-seated brain lesions treated with different tubular retraction systems: a systematic review and meta-analysis. World Neurosurg 143:537-545.e3
Mayfrank L, Kissler J, Raoofi R, Delsing P, Weis J, Küker W et al (1997) Ventricular dilatation in experimental intraventricular hemorrhage in pigs. Characterization of cerebrospinal fluid dynamics and the effects of fibrinolytic treatment. Stroke 28(1):141–148. https://doi.org/10.1161/01.str.28.1.141
Mayhall CG, Archer NH, Lamb VA, Spadora AC, Baggett JW, Ward JD et al (1984) Ventriculostomy-related infections. A prospective epidemiologic study. N Engl J Med 310(9):553–559. https://doi.org/10.1056/NEJM198403013100903
Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, Hope DT et al (2005) Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet 365(9457):387–397. https://doi.org/10.1016/S0140-6736(05)17826-X
Murphy RK, Liu B, Srinath A, Reynolds MR, Liu J, Craighead MC et al (2015) No additional protection against ventriculitis with prolonged systemic antibiotic prophylaxis for patients treated with antibiotic-coated external ventricular drains. J Neurosurg 122(5):1120–1126. https://doi.org/10.3171/2014.9.JNS132882
Naff N, Williams MA, Keyl PM, Tuhrim S, Bullock MR, Mayer SA et al (2011) Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial. Stroke 42(11):3009–3016. https://doi.org/10.1161/STROKEAHA.110.610949
Naff NJ (1999) Intraventricular hemorrhage in adults. Curr Treat Options Neurol 1(3):173–178. https://doi.org/10.1007/s11940-999-0001-0
Nelson SE, Mould WA, Gandhi D, Thompson RE, Salter S, Dlugash R et al (2020) Primary intraventricular hemorrhage outcomes in the CLEAR III trial. Int J Stroke. https://doi.org/10.1177/1747493020908146
Nieuwkamp DJ, de Gans K, Rinkel GJ, Algra A (2000) Treatment and outcome of severe intraventricular extension in patients with subarachnoid or intracerebral hemorrhage: a systematic review of the literature. J Neurol 247(2):117–121. https://doi.org/10.1007/pl00007792
Nyquist PA, Carhuapoma JR (2009) Future therapy in intracerebral hemorrhage and intraventricular hemorrhage: aspiration and thrombolysis. In: Intracerebral hemorrhage. Cambridge University Press, Cambridge. https://doi.org/10.1017/CBO9780511691836.016
Oppong MD, Gembruch O, Herten A, Frantsev R, Chihi M, Dammann P, Hindy NE, Forsting M, Sure U, Jabbarli R (2017) Intraventricular hemorrhage due to subarachnoid hemorrhage: does the severity matter? World Neurosurg 111:e693–e702
Raza SM, Recinos PF, Avendano J, Adams H, Jallo GI, Quinones- Hinojosa A (2011) Minimally invasive trans-portal resection of deep intracranial lesions. Minim Invasive Neurosurg 54(1):5–11
Recinos PF, Raza SM, Jallo GI, Recinos R (2011) Use of a minimally invasive tubular retraction system for deep-seated tumors in pediatric patients. J Neursurg Pediatr 7(5):516–521
Root BK, Barrena BG, Mackenzie TA, Bauer DF (2016) Antibiotic impregnated external ventricular drains: meta and cost analysis. World Neurosurg 86:306–315. https://doi.org/10.1016/j.wneu.2015.09.032
Rymarczuk GN, Davidson L, Severson MA, Armonda RA (2015) Use of a minimally invasive retractor system for retrieval of intracranial fragments in wartime trauma. World Neurosurg 84(4):1055–1061
Schmidt DR, Waldeck H, Kao WJ (2009) Biological interactions on materials surfaces: protein absorption to biomaterials. Springer, New York
Shapiro SZ, Sabacinski KA, Mansour SA, Echeverry NB, Shah SS, Stein AA, Snelling BM (2020) Use of Vycor tubular retractors in the management of deep brain lesions: a review of current studies. World Neurosurg 133:283–290
Sheppard JP, Duong C, Lagman C, Patel K, Sun MZ, Prashant GN et al (2020) In Reply: systemic antimicrobial prophylaxis and antimicrobial-coated external ventricular drain catheters for preventing ventriculostomy-related infections: a meta-analysis of 5242 cases. Neurosurgery 86(2):E240–E243. https://doi.org/10.1093/neuros/nyz494
Shibahashi K, Sugiyama K, Okura Y, Hoda H, Hamabe Y (2018) Intraventricular hemorrhage after head injury: a multicenter, retrospective, cohort study. World Neurosurg 114:e350–e355. https://doi.org/10.1016/j.wneu.2018.02.183
Soler GJ, Bao M, Jaiswal D, Zaveri HP, DiLuna ML, Grant RA, Hoshino K (2018) A review of cerebral shunts, current technologies, and future endeavors. Yale J Biol Med 91(3):313–321
Song P, Duan FL, Cai Q, Wu JL, Chen XB, Wang Y et al (2018) Endoscopic surgery versus external ventricular drainage surgery for severe intraventricular hemorrhage. Curr Med Sci 38(5):880–887. https://doi.org/10.1007/s11596-018-1957-3
Spazzapan Peter BR, Marjan Z (2016) External ventricular drainage infections: a single-centre experience on 100 cases. J Neurol Neurophysiol 7(4):392. https://doi.org/10.4172/2155-9562.1000392
Spiotta AM, Fiorella D, Vargas J, Khalessi A, Hoit D, Arthur A et al (2015) Initial multicenter technical experience with the Apollo device for minimally invasive intracerebral hematoma evacuation. Neurosurgery 11(Suppl 2):243–251. https://doi.org/10.1227/NEU.0000000000000698
Srinivasan VM, O’Neill BR, Jho D, Whiting DM, Oh MY (2014) The history of external ventricular drainage. J Neurosurg 120(1):228–236. https://doi.org/10.3171/2013.6.JNS121577
Steiner T, Diringer MN, Schneider D, Mayer SA, Begtrup K, Broderick J et al (2006) Dynamics of intraventricular hemorrhage in patients with spontaneous intracerebral hemorrhage: risk factors, clinical impact, and effect of hemostatic therapy with recombinant activated factor VII. Neurosurgery 59(4):767–773. https://doi.org/10.1227/01.NEU.0000232837.34992.32
Sweid A, Weinberg JH, Abbas R, El Naamani K, Tjoumakaris S, Wamsley C et al (2020) Predictors of ventriculostomy infection in a large single-center cohort. J Neurosurg 134(3):1–8
Tan AP, Svrckova P, Cowan F, Chong WK, Mankad K (2018) Intracranial hemorrhage in neonates: a review of etiologies, patterns and predicted clinical outcomes. Eur J Paediatr Neurol 22(4):690–717. https://doi.org/10.1016/j.ejpn.2018.04.008
Tan LA, Lopes DK, Munoz LF, Shah Y, Bhabad S, Jhaveri M et al (2016) Minimally invasive evacuation of intraventricular hemorrhage with the Apollo vibration/suction device. J Clin Neurosci Off J Neurosurg Soc Australas 27:53–58. https://doi.org/10.1016/j.jocn.2015.08.037
Tavakoli BGX, Taylor RH, Kang JU, Bocter EM (2014) Detecting occlusion inside a ventricular catheter using photo-acousting imaging through skull. Proc SPIE Int Soc Opt Eng. https://doi.org/10.1117/12.2040805
Tavakoli S, Peitz G, Ares W, Hafeez S, Grandhi R (2017) Complications of invasive intracranial pressure monitoring devices in neurocritical care. Neurosurg Focus 43(5):E6. https://doi.org/10.3171/2017.8.FOCUS17450
Thabet AM, Kottapally M, Hemphill CJ III (2017) Management of intracerebral hemorrhage. Handb Clin Neurol 140:177–194
Thamjamrassri T, Yuwapattanawong K, Chanthima P, Vavilala MS, Lele AV (2020) A narrative review of the published literature, hospital practices, and policies related to external ventricular drains in the United States: the External Ventricular Drain Publications, Practices, and Policies (EVDPoP) Study. J Neurosurg Anesthesiol. https://doi.org/10.1097/ANA.0000000000000694
Thomale UW (2015) Intracranial ventricular catheter placement with a smartphone assisted instrument. Methods Mol Biol 1256:405–417. https://doi.org/10.1007/978-1-4939-2172-0_27
Tomei KL (2017) The evolution of cerebrospinal fluid shunts: advances in technology and technique. Pediatr Neurosurg 52(6):369–380
Troiani Z, Ascanio LC, Yaeger KA, Ali M, Kellner CP (2021) Minimally invasive surgiscopic evacuation of intracerebral hemorrhage. J Neurointerv Surg 13(4):400
Tuhrim S, Horowitz DR, Sacher M, Godbold JH (1999) Volume of ventricular blood is an important determinant of outcome in supratentorial intracerebral hemorrhage. Crit Care Med 27(3):617–621. https://doi.org/10.1097/00003246-199903000-00045
Valdez Sandoval P, Hernández Rosales P, Quiñones Hernández DG, Chavana Naranjo EA, García Navarro V (2019) Intraventricular hemorrhage and posthemorrhagic hydrocephalus in preterm infants: diagnosis, classification, and treatment options. Child’s nervous system: ChNS. J Int Soc Pediatr Neurosurg 35(6):917–927. https://doi.org/10.1007/s00381-019-04127-x
van Solinge TS, Muskens IS, Kavouridis VK, Gormley WB, Mekary RA, Broekman MLD et al (2020) Fibrinolytics and intraventricular hemorrhage: a systematic review and meta-analysis. Neurocrit Care 32(1):262–271. https://doi.org/10.1007/s12028-019-00786-5
Wang T, Zhao QJ, Gu JW, Shi TJ, Yuan X, Wang J et al (2019) Neurosurgery medical robot Remebot for the treatment of 17 patients with hypertensive intracerebral hemorrhage. Int J Med Robot 15(5):e2024. https://doi.org/10.1002/rcs.2024
Wang X, Dong Y, Qi XQ, Li YM, Huang CG, Hou LJ (2013) Clinical review: efficacy of antimicrobial-impregnated catheters in external ventricular drainage—a systematic review and meta-analysis. Crit Care 17(4):234. https://doi.org/10.1186/cc12608
Weisenberg SH, TerMaath SC, Seaver CE, Killeffer JA (2016) Ventricular catheter development: past, present, and future. J Neurosurg 125(6):1504–1512. https://doi.org/10.3171/2015.12.JNS151181
Xu LC, Bauer JW, Siedlecki CA (2014) Proteins, platelets, and blood coagulation at biomaterial interfaces. Colloids Surf B 124:49–68. https://doi.org/10.1016/j.colsurfb.2014.09.040
Yamaki VN, Cavalcanti DD, Figueiredo EG (2019) Delayed ischemic neurologic deficit after aneurysmal subarachnoid hemorrhage. Asian J Neurosurg 14(3):641–647. https://doi.org/10.4103/ajns.AJNS_15_19
Young WB, Lee KP, Pessin MS, Kwan ES, Rand WM, Caplan LR (1990) Prognostic significance of ventricular blood in supratentorial hemorrhage: a volumetric study. Neurology 40(4):616–619. https://doi.org/10.1212/wnl.40.4.616
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Carpenter, A.B., Lara-Reyna, J., Hardigan, T. et al. Use of emerging technologies to enhance the treatment paradigm for spontaneous intraventricular hemorrhage. Neurosurg Rev 45, 317–328 (2022). https://doi.org/10.1007/s10143-021-01616-z
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DOI: https://doi.org/10.1007/s10143-021-01616-z