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Current Pharmaceutical Biotechnology

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ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

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Review Article

Beta-glucans is a Potential Inhibitor of Ovarian Cancer: Based on Molecular and Biological Aspects

Author(s): Fatemeh Sadoughi, Zatollah Asemi, Jamal Hallajzadeh*, Mohammad Ali Mansournia and Bahman Yousefi

Volume 23, Issue 9, 2022

Published on: 10 August, 2021

Page: [1142 - 1152] Pages: 11

DOI: 10.2174/1389201022666210810090728

Price: $65

Abstract

Ovarian cancer is a lethal type of cancer which is initiated to the ovaries and affects 1 out of every 75 women. Due to the high number of deaths (almost 152,000) related to this cancer, it seems that novel efficient therapeutic methods are required in this field. Beta-glucans are a type of glucose linear polymers which have been proven to have a lot of advantageous activities. Recently, investigations have declared that these polysaccharides have the potential to be used as anti-cancer drugs. These agents are able to affect several mechanisms such as inflammation and apoptosis, and that is how cancers are prone to be affected by them. In this review, we attempt to investigate the role of beta-glucans on ovarian cancer. We hope that this paper would give some novel insights into the field of ovarian cancer treatment.

Keywords: Beta-glucans, ovarian cancer, apoptosis, signaling, anti-cancer, ovaries.

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