Abstract
In this paper, a composite based on chitosan and cobalt phthalocyanine immobilized onto a glassy carbon electrode is presented for the sensitive determination of sulfanilamide in pharmaceutical and urine samples. The modification performed on the electrode surface, by the deposition of this composite, exhibits an irreversible anodic peak at 0.97 V vs. Ag/AgCl, KClsat in phosphate buffer at pH 7.00 for sulfanilamide. Results show that peak potential is influenced linearly by the pH of the supporting electrolyte, exhibiting a slope of 0.054 V/pH. Using differential pulse voltammetry, detection of sulfanilamide was possible in a linear range from 1.00 to 53.00 μmol dm−3 with a detection limit and quantification limit of 0.27 and 0.91 μmol dm−3, respectively. Importantly, the sensor showed practical applications as an analytical tool for the quantification of sulfanilamide in pharmaceutical formulations and urine samples. The electrochemical approach detailed here has been validated to drug samples using a spectrophotometric method. The method proposed presents good linearity, low quantification and detection limits being of excellent applicability in pharmaceutical and urine samples.
Graphic abstract
Similar content being viewed by others
References
Sui YF, Li D, Wang J, Bheemanaboina RRY, Ansari MF, Gan LL, Zhou CH (2020) Bioorg Med Chem Lett 30:126982
Petrović S, Tačić A, Savić S, Nikolić V, Nikolić L, Savić S (2017) Saudi Pharm J 25:1194
Al SM, Ghemrawi R (2020) Microbiomics. Academic Press, p 279
Medina MJ, Legido-Quigley H, Hsu LY (2020) In: global health security. Springer, p 209
Ahamad A, Madhav S, Singh AK, Kumar A, Singh P (2019) In: sensors in water pollutants monitoring: role of material. Springer, p 21
Meng T, Cheng W, Wan T, Wang M, Ren J, Li Y, Huang C (2019) Environ Technol 23:1
Dórea NR, Santos RHT, Fraga LE, Garcia CAB, Garcia HL, Arguelho M de LP de M (2014) In: Proceedings of Safety, Health and Environment World Congress, p 87
Yuan SF, Liu ZH, Yin H, Dang Z, Wu PX, Zhu NW, Lin Z (2019) Sci Total Environ 653:815
Muhammad J, Khan S, Su JQ, Hesham AEL, Ditta A, Nawab J, Ali A (2020) J Soils Sediments 20:486
Albero B, Tadeo JL, Miguel E, Pérez RA (2019) Anal Bioanal Chem 411:6129
Chen Y, Xia S, Han X, Fu Z (2020) J Anal Methods Chem 2020:1
Maggira M, Deliyanni EA, Samanidou VF (2019) Molecules 24:2086
Sereshti H, Khosraviani M, Amini-fazl MS (2014) Talanta 121:199
López-Sánchez M, Ruedas-Rama MJ, Ruiz-Medina A, Molina-Díaz A, Ayora-Cañada MJ (2008) Talanta 74:1603
Nevado JJB, Salinas F, de Orbe PI, Capitan-Vallvey LF (1991) J Pharm Biomed Anal 9:117
Mohammad-Razdari A, Ghasemi-Varnamkhasti M, Izadi Z, Rostami S, Ensafi AA, Siadat M, Losson E (2019) J Food Compos Anal 82:103252
He B, Li M (2018) Anal Bioanal Chem 410:7671
Canales C, Ramos D, Fierro A, Antilén M (2019) Electrochim Acta 318:847
Ferraz BRL, Guimarães T, Profeti D, Profeti LPR (2018) J Pharm Anal 8:55
Ferraz BRL, Profeti D, Profeti LPR (2018) J Solid State Electrochem 22:339
Won SY, Chandra P, Hee TS, Shim YB (2013) Biosens Bioelectron 39:204
Chen S, Wang C, Zhang M, Zhang W, Qi J, Sun X, Wang L, Li J (2020) J Hazard Mater 390:122157
He B-S, Yan X-H (2018) Sensors 18:846
Li H (2019) Int J Electrochem Sci 14:7858
Wei X, Xu X, Qi W, Wu Y, Wang L (2017) Prog Nat Sci Mater Int 27:374
Tadi KK, Motghare RV, Ganesh V (2014) Electroanalysis 26:2328
Bueno AM, Contento AM, Ríos Á (2013) Anal Methods 5:6821
Gondim CS, Durán GM, Contento AM, Ríos Á (2018) Food Anal Methods 11:1711
Vanoni CR, Winiarski JP, Nagurniak GR, Magosso HA, Jost CL (2019) Electroanalysis 31:867
De Sousa Luz RA, Martins MVA, Magalhães JL, Siqueira JR, Zucolotto V, Oliveira ON, Crespilho FN, Da Silva WC (2011) Mater Chem Phys 130:1072
Kozub BR, Compton RG (2010) Sens Actu B 147:350
Rana A, Baig N, Saleh TA (2019) J Electroanal Chem 833:313
Da SIS, Araújo MFA, Ferreira HA, Varela JDJG, Tanaka SMCN, Tanaka AA, Angnes L (2011) Talanta 83:1701
Pereira LNDS, Da Silva IS, Araújo TP, Tanaka AA, Angnes L (2016) Talanta 154:249
Ferreira APM, dos Santos Pereira LN, da Silva IS, Tanaka SMCN, Tanaka AA, Angnes L (2014) Electroanalysis 26:2138
Santos AM, Wong A, Cincotto FH, Moraes FC, Fatibello-Filho O (2019) Microchim Acta 186:148
Farmacopéia ANDVS (2010) Brazilian Pharmacopoeia, 5th edn. ANVISA, Brasília
Li H, Kuang X, Shen X, Jianwei Z, Zhang B, Li H (2019) Int J Electrochem Sci 14:7858
Ruas De Souza AP, Felix FS, Castro PS, Angnes L, Bertotti M (2016) Anal Methods 8:1078
Singh P, Kushwaha CS, Singh VK, Dubey GC, Shukla SK (2021) Sens Actu B 342:130042
Gomes RN, Sousa CP, Casciano PNS, Ribeiro FWP, Morais S, de Lima-Neto P, Correia AN (2018) Mater Sci Eng C 88:148
Laube N, Mohr B, Hesse A (2001) J Cryst Growth 233:367
Acknowledgements
The authors are grateful for the financial support provided by the Brazilian agencies:
National Council for Scientific and Technological Development—CNPq (grant no. 205220/2018-5, 133321/2019-3); Foundation for the Support of Research, Scientific and Technological Development of Maranhão–FAPEMA (grant no. 01372/17-UNIVERSAL). Coordination of Superior Level Staff Improvement—CAPES (grant no. 88887.472618/2019-00-PROCAD-AM, 88882.445688/2019-01).
H.-B. Kraatz is grateful for financial support from Natural Sciences and Engineering Research Council of Canada (RGPIN-2016-06122) and from the University of Toronto Scarborough.
Author information
Authors and Affiliations
Corresponding authors
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Supplementary Information
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
de Moura Junior, F.G., Veloso, W.B., de Oliveira Junior, J.A. et al. Voltammetric determination of sulfanilamide using a cobalt phthalocyanine chitosan composite. Monatsh Chem 152, 895–902 (2021). https://doi.org/10.1007/s00706-021-02812-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00706-021-02812-9