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A photoelectrochemical aptasensor of ciprofloxacin based on Bi24O31Cl10/BiOCl heterojunction

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Abstract

A photoelectrochemical (PEC) aptasensor was designed and constructed by Bi24O31Cl10/BiOCl heterojunction as a photoelectric active material for realizing the determination of trace ciprofloxacin (CIP) in water. Compared with Bi24O31Cl10, Bi24O31Cl10/BiOCl heterojunction possessed the improvement of light harvesting and the enhancement of photocurrent signal. The formation of heterojunction between Bi24O31Cl10 and BiOCl can accelerate the transportation efficiency and inhibit the recombination rate of photoinduced carriers. Based on the excellent PEC performance, CIP aptamer was introduced on the modified Bi24O31Cl10/BiOCl/indium tin oxide (ITO) electrode for fabricating a PEC aptasensor. Owing to the combination between aptamer and CIP, CIP-aptamer complex can block the transfer of charge, leading to the reduction of photocurrent response. The PEC aptasensor possessed high sensitivity with a wide detection range (5.0~1.0 × 104 ng L−1) and a low detection limit (1.67 ng L−1, S/N = 3). The PEC aptasensor with good selectivity and reproducibility has been applied to the determination of CIP in water.

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Funding

This work has been financially supported by the High-tech Research Key laboratory of Zhenjiang (Grant No. SS2018002), a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions, and the Jiangsu Collaborative Innovation Center of Technology and Material for Water Treatment (XTCXSZ2019-1).

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Institute for Energy Research, Jiangsu University, Zhenjiang, 212013, China

    Mengying Yang, Yun Chen, Pengcheng Yan, Jintao Dong, Wei Duan, Li Xu & Henan Li

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  1. Mengying Yang
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  2. Yun Chen
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  4. Jintao Dong
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  6. Li Xu
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  7. Henan Li
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Correspondence to Henan Li.

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Yang, M., Chen, Y., Yan, P. et al. A photoelectrochemical aptasensor of ciprofloxacin based on Bi24O31Cl10/BiOCl heterojunction. Microchim Acta 188, 289 (2021). https://doi.org/10.1007/s00604-021-04952-5

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