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Breast carcinomas of low malignant potential

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Abstract

Some breast carcinomas have a very low likelihood of metastasis to regional lymph nodes and distant sites and may be considered carcinomas of low malignant potential. In this article, we review the clinical, pathologic, immunophenotypic, and molecular features of selected breast carcinomas of low malignant potential including low-grade adenosquamous carcinoma, fibromatosis-like metaplastic carcinoma, encapsulated papillary carcinoma, solid papillary carcinoma, and tall cell carcinoma with reversed polarity.

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Authors and Affiliations

  1. Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School; Breast Oncology Program, Dana-Farber/Brigham and Women’s Cancer Center, 75 Francis Street, Boston, MA, 02115, USA

    Stuart J. Schnitt

  2. Department of Pathology and Neuropathology, Tübingen University Hospital and Comprehensive Cancer Center Tübingen-Stuttgart, Tübingen, Germany

    Falko Fend

  3. Mammography Screening Reference Centres Muenster and Berlin, Department of Surgical Pathology, Dietrich Bonhoeffer Medical Centre, Neubrandenburg, Germany

    Thomas Decker

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  1. Stuart J. Schnitt
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Correspondence to Stuart J. Schnitt.

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Schnitt, S.J., Fend, F. & Decker, T. Breast carcinomas of low malignant potential. Virchows Arch 480, 5–19 (2022). https://doi.org/10.1007/s00428-021-03163-w

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