Three unprecedented selective bioconjugation methods for serine, methionine and lysine have been realized. Specifically, chemoselectivity for serine, site-selectivity for methionine and site-specificity for lysine were achieved.
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Acknowledgements
This first-time Year in Review in Nature Reviews Chemistry is dedicated to the memory of the author’s MSc supervisor, Prof. George Foscolos, for his commitment to student progression will echo forever. The author thanks the groups of Professors Baran, MacMillan and Bode, whose work inspired her to write this year in review.
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Koperniku, A. A series of selective events. Nat Rev Chem 5, 674–675 (2021). https://doi.org/10.1038/s41570-021-00317-x
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DOI: https://doi.org/10.1038/s41570-021-00317-x
