ReviewFatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers
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open access
Arachidnoic acid,
Cardiovascular disease
Docosahexaenoic acid
FABPs
FAT/CD36
FABPpm
n-3/n-6 Fatty acids
Long-chain fatty acids
Neurology
NEFAs
Toll-like receptors
VEGF
Alzheimer's disease
Inflammation
LCPUFAs
Blood brain barrier
FATPs
Endothelium
COX
Prostaglandins
Cancers
Brain
Abbreviations
AD
Alzheimer's disease
ANGPT2
Angiopoietin 2
ANGPTL4
Angiopoietin-like 4
ARA
Arachidonic acid, 20:4n-6
BBB
Blood-brain-barrier
CVD
Cardiovascular disease
CD36
Cluster of differentiation 36
DHA
Docosahexaenoic acid 22:6n-3
EC
endothelial cell
eNOS
Endothelial nitric oxide synthase
EPA
Eicosapentaenoic acid, 20:5n-3
FABP
Fatty acid-binding protein
FAT
fatty acid translocase
FABPpm
Plasma membrane fatty acid-binding protein
FATP
Fatty acid transport protein
LA
Linoleic acid,18:2n-6
LCFA
Long-chain fatty acid
LCPUFA
Long-chain polyunsaturated fatty acid
Mfsd2a
Major facilitator superfamily domain-containing protein 2a
mTOR
Mammalian endothelial target of rapamycin
MDSC
Myeloid derived suppressor cells
NEFA
Non-esterified fatty acid
NPC
Niemann–Pick disease type C
PPARα
Peroxisome proliferator-activated receptor-alpha
PPARγ
Peroxisome proliferator-activated receptor-gamma
PLA2
Phospholipases A2
PMN-MDSC
Polymorphonuclear myeloid-derived suppressor cells
PUFA
Polyunsaturated fatty acid
ROS
Reactive oxygen species
TLR
Toll-like receptor
VEGF
Vascular endothelial growth factor
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© 2021 The Author(s). Published by Elsevier Ltd.