Journal of the American Academy of Child & Adolescent Psychiatry
EditorialEditorial: Toward Neurobiological-Based Treatments of Depression and Anxiety: A Potential Case for the Nucleus Accumbens
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2022, Current Opinion in Endocrine and Metabolic ResearchCitation Excerpt :Regarding mood disorders, the nucleus accumbens is another neuroanatomical relevant substrate with a prominent expression of the δ subunit. It is a crucial hub of the reward circuit, which is implicated in the anhedonia associated with depression and other stress-related mood disturbances [56]. We previously reported the tonic current of MSNs, which is mediated by α4βδ GABAARs to be increased by activation of the dopamine (D1) GPCR [57].
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This work was supported by the National Institute of Mental Health under K01MH117442 and the Ray and Dagmar Dolby Family Fund. The content is solely the responsibility of the author and does not necessarily represent the official views of the National Institutes of Health.
Disclosure: Dr. Ho has reported no biomedical financial interests or potential conflicts of interest.
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