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Positronium in Biosystems and Medicine: A New Approach to Tumor Diagnostics Based on Correlation between Oxygenation of Tissues and Lifetime of the Positronium Atom

  • AQUEOUS SOLUTIONS IN BIOLOGICAL SYSTEMS
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Abstract

Current trends in development of positron annihilation tomography (change-over to total body tomography, new image reconstruction methods based on Time-of-Flight techniques and 3γ annihilation events) are discussed. They open up unique possibilities of identifying both the annihilation point of Ps atoms and their lifetime in the tissues of the organism under study (Ps imaging). Our experimental data are presented that demonstrate a relationship between the Ps lifetime and the degree of oxygenation of tissues, which is actually a new additional method for tumor diagnostics using е+е– annihilation.

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ACKNOWLEDGMENTS

The experimental work was done at facilities of the Research Equipment Sharing Center KAMIKS (http://kamiks.itep.ru/), ITEP, NRC “Kurchatov Institute”.

Funding

The work was supported by the Russian Foundation for Basic Research, project no. 20-14-50150\20.

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Authors and Affiliations

  1. National Research Center “Kurchatov Institute”–Alikhanov Institute of Theoretical and Experimental Physics, 117218, Moscow, Russia

    S. V. Stepanov & V. M. Byakov

  2. Faculty of Chemistry, Lomonosov Moscow State University, 119991, Moscow, Russia

    S. V. Stepanov & V. M. Byakov

  3. Mendeleev University of Chemical Technology of Russia, 125047, Moscow, Russia

    V. M. Byakov

  4. The Catholic University of America, DC 20064, Washington, USA

    P. S. Stepanov

Authors
  1. S. V. Stepanov
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  2. V. M. Byakov
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  3. P. S. Stepanov
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Correspondence to S. V. Stepanov.

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Translated by M. Potapov

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Stepanov, S.V., Byakov, V.M. & Stepanov, P.S. Positronium in Biosystems and Medicine: A New Approach to Tumor Diagnostics Based on Correlation between Oxygenation of Tissues and Lifetime of the Positronium Atom. Phys. Wave Phen. 29, 174–179 (2021). https://doi.org/10.3103/S1541308X21020138

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