International Heart Journal
Online ISSN : 1349-3299
Print ISSN : 1349-2365
ISSN-L : 1349-2365
Clinical Studies
Deep Sedation with Intravenous Anesthesia Is Associated with Outcome in Patients Undergoing Cryoablation for Paroxysmal Atrial Fibrillation
Ting-Yung Chang, Li-Wei Lo, Abigail Louise D. Te, Sugako Ishigaki, Akira Maesato, Yenn-Jiang Lin, Shih-Lin Chang, Yu-Feng Hu, Fa-Po Chung, Chin-Yu Lin, Tze-Fan Chao, Jo-Nan Liao, Ta-Chuan Tuan, Ling Kuo, Cheng-I Wu, Chih-Min Liu, Ankit Jain, Isaiah C. Lugtu, Satoshi Higa, Shih-Ann Chen
Author information
Keywords: Ablation, Deep sedation, Cryoballoon, Recurrence
JOURNAL FREE ACCESS

2021 Volume 62 Issue 4 Pages 779-785

Browse “Advance online publication” version
Details
Download PDF (126K)
Download citation RIS

(compatible with EndNote, Reference Manager, ProCite, RefWorks)

BIB TEX

(compatible with BibDesk, LaTeX)

Text
How to download citation
Contact us
Abstract

Whether deep sedation with intravenous anesthesia will affect the recurrence after cryoballoon ablation (CBA) of paroxysmal atrial fibrillation (AF) is yet to be examined. Thus, in this study, we hypothesize that there is difference in terms of the recurrence between local anesthesia and deep sedation with intravenous anesthesia after an index ablation procedure.

In total, 109 patients were enrolled and received CBA, of which 68 (58.2 years) patients underwent pulmonary vein (PV) isolation with a local anesthesia (group 1) and 41 patients (63.2 years) underwent PV isolation with deep sedation using intravenous anesthesia (group 2).

During the index procedure, isolation of all major PVs was achieved in 66 patients in group 1 and in 41 patients in group 2. There was no difference in non-PV triggers between the two groups. The periprocedural complication was found to be similar between the two groups (2.9% in group 1 and 4.9% in group 2). Further, 17 patients in group 1 and 4 patients in group 2 experienced recurrences after a follow-up of 19.3 months (P = 0.019). Repeat procedures revealed similar PV reconnection rates between the two groups. It has also been noted that the number of reconnected PV and incidence of atypical flutter seem to increase in group 1.

Deep sedation with intravenous anesthesia during CBA for paroxysmal AF is safe and had a better long-term outcome than those with local anesthesia.

Content from these authors
© 2021 by the International Heart Journal Association
Previous article Next article
Favorites & Alerts

Recently viewed articles
Predecessor

Japanese Heart Journal

Share this page
feedback
 Top