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Modeling of Retinal Degeneration

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Bulletin of Experimental Biology and Medicine Aims and scope

We developed a model of retinal degeneration in rabbits based on exposure to light with a wavelength of 405 nm. This model allows reproducing structural and functional disorders in the central parts of the retina, including primarily degeneration of the outer layers of the retina (retinal pigment epithelium and layer of photoreceptor cells), and is designed to study the mechanisms of formation, progression and effectiveness of new drugs and methods of treatment of degenerative diseases of the retina.

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Authors and Affiliations

  1. State Research Test Institute of Military Medicine, Ministry of Defense of the Russian Federation, St. Petersburg, Russia

    A. A. Suetov, S. I. Alekperov, M. A. Odinokaya & A. A. Kostina

  2. St. Petersburg Branch of S. N. Fyodorov Eye Microsurgery, St. Petersburg, Russia

    A. A. Suetov & E. V. Boiko

  3. Department of Ophthalmology, I. I. Mechnikov North-West State Medical University, St. Petersburg, Russia

    E. V. Boiko

  4. Department of Ophthalmology, S. M. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation, St. Petersburg, Russia

    E. V. Boiko

Authors
  1. A. A. Suetov
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  2. E. V. Boiko
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  3. S. I. Alekperov
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  4. M. A. Odinokaya
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  5. A. A. Kostina
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Corresponding author

Correspondence to A. A. Suetov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 171, No. 2, pp. 259-264, February, 2021

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Suetov, A.A., Boiko, E.V., Alekperov, S.I. et al. Modeling of Retinal Degeneration. Bull Exp Biol Med 171, 286–291 (2021). https://doi.org/10.1007/s10517-021-05213-4

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  • DOI: https://doi.org/10.1007/s10517-021-05213-4

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