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Methods for the Preparation of 3-Nitrobenzofurans

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Chemistry of Heterocyclic Compounds Aims and scope

The review summarizes the existing methods for the synthesis of 3-nitrobenzofurans and their polycondensed derivatives which are valuable substrates for dearomatization of the furan ring. The main attention is paid to the electrophilic nitration of 3-unsubstituted benzofurans and the preparation of 5-amino- and 5-hydroxy-3-nitrobenzofurans via the Nenitzescu indole synthesis from quinones or quinone monoimines and β-nitroenamines.

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Authors and Affiliations

  1. Samara State Technical University, 244 Molodogvardeyskaya St, Samara, 443100, Russia

    Vitaly А. Osyanin, Dmitry V. Osipov, Darya А. Rashchepkina & Yuri N. Klimochkin

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  1. Vitaly А. Osyanin
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  2. Dmitry V. Osipov
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  3. Darya А. Rashchepkina
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Correspondence to Vitaly А. Osyanin or Dmitry V. Osipov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2021, 57(6), 615–623

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Osyanin, V.А., Osipov, D.V., Rashchepkina, D.А. et al. Methods for the Preparation of 3-Nitrobenzofurans. Chem Heterocycl Comp 57, 615–623 (2021). https://doi.org/10.1007/s10593-021-02957-9

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