Polyamines are a growing class of medically and agriculturally active biomolecules that have traditionally been difficult to source. Now, a bio-based platform for high-level production of diverse polyamines has been realized, showing the versatility of biocatalysis and the utility of conceptualizing metabolism as distinct modules.
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References
Handa, A. K., Fatima, T. & Mattoo, A. K. Front. Chem. 6, 10 (2018).
Qin, J. et al. Nat. Catal. https://doi.org/10.1038/s41929-021-00631-z (2021).
Qin, J. et al. Nat. Commun. 6, 8224 (2015).
Li, L. et al. ACS Sustain. Chem. Eng. 8, 2147–2157 (2020).
Atsumi, S., Hanai, T. & Liao, J. C. Nature 451, 86–89 (2008).
Ajikumar, P. K. et al. Science 330, 70–74 (2010).
Li, Y. et al. Proc. Natl Acad. Sci. USA 115, E3922–E3931 (2018).
Yang, J. E. et al. Nat. Commun. 9, 79 (2018).
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Reed, K.B., Alper, H.S. Modular biocatalysis for polyamines. Nat Catal 4, 449–450 (2021). https://doi.org/10.1038/s41929-021-00636-8
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DOI: https://doi.org/10.1038/s41929-021-00636-8