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RETRACTED ARTICLE: TWO MIXED-LIGAND Cu(II) COORDINATION POLYMERS: PROTECTIVE EFFECT ON SEPSIS BY REDUCING AN EXCESSIVE INFLAMMATORY RESPONSE

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This article was retracted on 01 March 2023

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Abstract

By the reaction of a rigid π-conjugated H4L linker (5,5′-(1,3,6,8-tetraoxobenzo[lmn][3],[8]phenanthroline-2-7-diyl)bis-1,3-benzenedicarboxylic acid), Cu(NO3)2, and N-donor auxiliary linkers, two new Cu-based coordination polymers (CPs), namely {[Cu(L)0.5(1,4-bib)(H2O)2]·0.5H2O}n (1) and {[Cu(H2L)(4,4′-bibp)(H2O)2]}n (2) {1,4-bib = 1,4-bis(1-imidazolyl)benzene, 4,4′-bibp = 4,4′-bis(imidazolyl)biphenyl} are synthesized under solvothermal conditions and characterized. Furthermore, the protective effect of compounds 1 and 2 on the sepsis mice model is evaluated and the related mechanism is explored. Firstly, the CFU counting assay is performed to detect the bactericidal effect of compounds 1 and 2 in vivo. Then, the ELISA assay is conducted to measure the release of interleukin-1β (IL-1β) and interleukin-6 (IL-6) into the plasma after treatment with the compounds.

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Authors and Affiliations

  1. Department of Emergency, The Second Affiliated Hospital of Air Force Military Medical University, Xi′an, Shaanxi, People’s Republic of China

    G. -Q. Fu, J. -J. Yao, B. Ren & X. -F. Zan

  2. Hubei College of Chinese Medicine, Jingzhou, Hubei, People’s Republic of China

    Y. Fang

  3. Department of Medicine, Capital Medical University, Beijing, People’s Republic of China

    E. -L. Liu

  4. Zhongshan Hospital, Xiamen University, Xiamen, Fujian, People’s Republic of China

    M. -J. Chen

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  1. G. -Q. Fu
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  2. Y. Fang
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  4. B. Ren
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  5. X. -F. Zan
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  6. E. -L. Liu
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  7. M. -J. Chen
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Corresponding author

Correspondence to M. -J. Chen.

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Additional information

Text © The Author(s), 2021, published in Zhurnal Strukturnoi Khimii, 2021, Vol. 62, No. 5, pp. 870-876.https://doi.org/10.26902/JSC_id69930

This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1134/S0022476623030162"

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Fu, G.Q., Fang, Y., Yao, J.J. et al. RETRACTED ARTICLE: TWO MIXED-LIGAND Cu(II) COORDINATION POLYMERS: PROTECTIVE EFFECT ON SEPSIS BY REDUCING AN EXCESSIVE INFLAMMATORY RESPONSE. J Struct Chem 62, 810–816 (2021). https://doi.org/10.1134/S0022476621050176

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  • DOI: https://doi.org/10.1134/S0022476621050176

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