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Phytochemical Analysis of Polyphenol Secondary Metabolites in Cloudberry (Rubus Chamaemorus L.) Leaves

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Phytochemical analysis of cloudberry leaves isolated one new (1) and four well-known compounds (2-5) and established their structures. Compounds 1 (4-O-α-L-arabinofuranosylellagic acid) and 2 [(–)-epicatechin] belonged to the tannin class. The rest of the isolated compounds were the flavonoid glucuronic glycosides quercetin 3-O-β-D-glucuronide (3), quercetin 3-O-β-D-2′′-galloylglucuronide (4), and kaempferol 3-O-β-D-glucuronide (5). Compounds 4 and 5 were isolated from Rubus chamaemorus L. for the first time. Predictions of the biological activity spectra for isolated 1-5 using the PASS program provided insights regarding the most promising directions for studying their biological activity.

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Authors and Affiliations

  1. St. Petersburg State Chemical Pharmaceutical University, Ministry of Health of the Russian Federation, 14A Prof. Popova St., St. Petersburg, 197376, Russia

    A. K. Whaley, A. O. Ponkratova, A. A. Orlova & V. G. Luzhanin

  2. St. Petersburg State University, 7/9 Universitetskaya Naberezhnaya, St. Petersburg, 199034, Russia

    E. B. Serebryakov & S. N. Smirnov

  3. Heinrich Heine University, 1 Heinrich-Heine-Allee, 40213, Dusseldorf, Germany

    P. Proksh

  4. V. N. Orekhovich Institute of Biomedical Chemistry, 10/8 Pogodinskaya St., Moscow, 119121, Russia

    N. S. Ionov & V. V. Poroikov

Authors
  1. A. K. Whaley
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  2. A. O. Ponkratova
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  3. A. A. Orlova
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  4. E. B. Serebryakov
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  5. S. N. Smirnov
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  6. P. Proksh
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  7. N. S. Ionov
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  8. V. V. Poroikov
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  9. V. G. Luzhanin
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Corresponding author

Correspondence to A. O. Ponkratova.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 55, No. 3, pp. 22 – 27, March, 2021.

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Whaley, A.K., Ponkratova, A.O., Orlova, A.A. et al. Phytochemical Analysis of Polyphenol Secondary Metabolites in Cloudberry (Rubus Chamaemorus L.) Leaves. Pharm Chem J 55, 253–258 (2021). https://doi.org/10.1007/s11094-021-02407-y

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  • DOI: https://doi.org/10.1007/s11094-021-02407-y

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