Interest has been growing in the development of medical radioisotopes used for noninvasive nuclear medicine imaging of disease and cancer therapy. Especially the development of an alternative production scheme of ⁹⁹Mo, the mother radioisotope of ^99mTc used for imaging, is required, because the current supply chain of the reactor product ⁹⁹Mo is fragile worldwide. We have proposed a new production scheme of ⁹⁹Mo as well as therapeutic radioisotopes, such as ⁶⁴Cu and ⁶⁷Cu, using accelerator neutrons provided by the ^natC(d,n) reaction. Based on this scheme we have obtained high-quality ^99mTc, ⁶⁴Cu, and ⁶⁷Cu suitable for clinical use by developing both production and separation methods of the radioisotopes. We proposed a new facility to constantly and reliably produce a wide variety of high-quality, carrier-free radioisotopes, including ⁹⁹Mo, with accelerator neutrons. We report on the development of the proposed scheme and future prospects of the facility toward the domestic production of medical radioisotopes.