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Recent advances in dearomatization of benzazoles, purines, and caffeine (microreview)

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Chemistry of Heterocyclic Compounds Aims and scope

Dearomatization reactions are well established in organic synthesis and other research fields usually leading to structurally diverse polycyclic molecules or complex heterocyclic frameworks. In this microreview, recent development of dearomative functionalization of benzazoles, purines, and caffeine via cycloaddition or addition reaction has been summarized. This will help researchers to find the potential scientific value of dearomatization reactions in drug discovery.

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Financial support by the National Natural Science Foundation of China (Nos. 81973453 and 22078192) and the Shanghai University of Engineering Science (No. cs1804003) is gratefully acknowledged.

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, 333 Longteng Road, Shanghai, 201620, China

    Liliang Huang & Huangdi Feng

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  1. Liliang Huang
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  2. Huangdi Feng
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Correspondence to Liliang Huang.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2021, 57(5), 525–527

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Huang, L., Feng, H. Recent advances in dearomatization of benzazoles, purines, and caffeine (microreview). Chem Heterocycl Comp 57, 525–527 (2021). https://doi.org/10.1007/s10593-021-02936-0

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  • DOI: https://doi.org/10.1007/s10593-021-02936-0

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