Thin films for the SiO2–P2O5–CaO–ZnO system were synthesized by the sol-gel method. The compositions and technology for producing thin-film materials on a silicon substrate (model substrate) were developed. The structure of the films was investigated by means of infrared spectroscopy and x-ray phase analysis. It was established that the concentration and contents of the components in the system influence the properties of thin-film materials. The obtained materials are biologically highly active. The composition for obtaining thin-film material with a higher biological activity was determined.
Similar content being viewed by others
References
A. Barba, A. Diez-Escudero, Y. Maazouz, et al., “Osteoinduction by foamed and 3D-printed calcium phosphate scaffolds: Effect of nanostructure and pore architecture,” ACS Appl. Mater. Interfaces, 9, 41722 – 41736 (2017).
O. S. Zaroog, M. A. Satgunam, and L. C.Wei, “Biomaterials for bone tissue engineering: properties and applications,” in: Reference Module in Materials Science and Materials Engineering, Elsevier, Cambridge (2019), p. 14.
S. H. Bjîrnîy, D. C. Bassett, S. Ucar, et al., “A correlative spatiotemporal microscale study of calcium phosphate formation and transformation within an alginate hydrogel matrix,” Acta Biomaterialia, No. 44, 254 – 266 (2016).
X. Li, M. Wang, Y. Deng, et al., “Fabrication and properties of Ca–P bioceramic spherical granules with interconnected porous structure,” ACS Biomater. Sci. Eng., 3(8), 1557 – 1566 (2017).
M. Jokinen and H. Rahial, Relation between Aggregation and Heterogeneity of Obtained Structure in Sol-Gel Derived CaO–P2O5–SiO2 , Kluwer Academic Publishers, Dordrecht (1998), pp. 159 – 167.
H. Li and J. Chang, “Stimulation of proangiogenesis by calcium silicate bioactive ceramic,” Acta Biomaterialia, No. 9, 5379 – 5389 (2013).
A. Ito, H. Kawamura, M. Otsuka, et al., “Zinc-releasing calcium phosphate for stimulating bone formation,” Mater. Sci. Eng. C, No. 22(1), 21 – 25 (2002).
Y. Castro, J. Mosa, and M. Aparicio, “Sol-gel hybrid membranes loaded with meso_macroporous SiO2, TiO2–P2O5 and SiO2–TiO2–P2O5 materials with high proton conductivity,” Mater. Chem. Phys., No. 149 – 150, 686 – 694 (2015).
L. P. Borilo, T. S. Petrovskaya, and E. S. Lyutova, “Synthesis and properties of thin films based on phases of the SiO2–P2O5–CaO system,” Inorg. Mater., 50(8), 874 – 877 (2014).
S. Bose, D. Banerjee, and A. Bandyopadhyay, “Introduction to biomaterials and devices for bone disorders,” in: Materials and Devices for Bone Disorders, Elsevier Inc., Cambridge (2017).
L. P. Borilo, V. V. Kozik, E. S. Lutova, et al., “Sol-gel production and properties of spherical biomaterials for the system TiO2–SiO2 /CaO,” Glass Ceram., 76(7 – 8), 315 – 320 (2019) [Steklo Keram., No. 8, 42 – 49 (2019)].
M. B. Fialko, Non-Isothermal Kinetics in Thermal Analysis [in Russian], Izd. Tomsk. Universiteta, Tomsk (1981).
T. Kokubo, H. Kushitani, and S. Sakka, “Solutions able to reproduce in vivo surface–structure changes in bioactive glass-ceramic,” Biomaterials, 24, 721 – 734 (1990).
R. K. Ayler, Chemistry of Silica [Russian translation], Mir, Moscow (1982).
N. Matsumoto, K. Yoshida, K. Hashimoto, and Y. Toda, “Thermal stability of β-tricalcium phosphate doped with monovalent metal,” Mater. Res. Bull., No. 44, 1889 – 1894 (2009).
K. H. Park, S. J. Kim, Y. H. Jeong, et al., “Fabrication and biological properties of calcium phosphate_chitosan composite coating on titanium in modified SBF,” Mater. Sci. Eng., 113 – 118 (2018).
D. Bellucci, R. Salvatori, A. Anesi, et al., “SBF assays, direct and indirect cell culture tests to evaluate the biological performance of bioglasses and bioglass-based composite: three paradigmatic cases,” Mater. Sci. Eng. C, 757 – 764 (2019).
L. P. Borilo, E. S. Lyutova, and L. N. Spivakova, “Study of biological properties of thin-film materials on the basis of the SiO2–P2O5–CaO system,” Key Eng. Mater., 683, 427 – 432 (2016).
This article was written as part of the scientific project No. 8.1.28.2020, fulfilled with the support of the TGU Competitiveness Enhancement Program.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Steklo i Keramika, No. 2, pp. 27 – 32, February, 2021.
Rights and permissions
About this article
Cite this article
Borilo, L.P., Lyutova, E.S. Sol-Gel Preparation and Properties of Thin-Film Biomaterials for the SiO2–P2O5–CaO–ZnO System. Glass Ceram 78, 63–67 (2021). https://doi.org/10.1007/s10717-021-00349-1
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10717-021-00349-1