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A New Phenanthrene Derivative from Pleione praecox

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Chemistry of Natural Compounds Aims and scope

A new phenanthrene, 2,6-dihydroxy-5,8-dimethoxyphenanthrene (1), was isolated from Pleione praecox. The structure of the new compound was determined on the basis of NMR (1D and 2D) and HR-ESI-MS data. The new compound was also evaluated for its α-glucosidase inhibitory activity. Compared with the positive control acarbose, the new compound exhibited appreciable effect.

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Acknowledgment

The research work was supported by the Program Innovative Research Team in Science and Technology in Yunnan Province (202005AE160004), Yunnan Provincial Science and the Technology Department (202005AF150043) and Foundation of Yunling Scholars in Yunnan Province (2019), the National Natural Science Foundation of China (21202066) and the Applied Basic Research Program of Yunnan Province [2017FE468(-025)], PhD student innovation fund Project (2021) and the Project for Excellent Young Teacher of Kunming Medical University (Nos. J130130661, 60118090145, 70120030505, and 6011521120).

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Authors and Affiliations

  1. School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, 650500, Kunming, P. R. China

    Yu-Peng Li, Ya-Ting Shao & Rong-Ping Zhang

  2. College of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicine Utilization, Yunnan University of Chinese Medicine, 650500, Kunming, P. R. China

    Rong-Ping Zhang

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  1. Yu-Peng Li
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  2. Ya-Ting Shao
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Correspondence to Rong-Ping Zhang.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2021, pp. 349–350.

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Li, YP., Shao, YT. & Zhang, RP. A New Phenanthrene Derivative from Pleione praecox. Chem Nat Compd 57, 409–411 (2021). https://doi.org/10.1007/s10600-021-03375-1

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  • DOI: https://doi.org/10.1007/s10600-021-03375-1

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