Abstract
Two excitation methods based on 2D normal mode were proposed using two piezoelectric transducers (PZTs) with opposite phase and in-phase to excite the two dimensional normal modes of (1, 1) and (2, 1), respectively. The theoretical models of the excitation modes were deduced by the wave equation. An ultrasonic separator was built and the acoustic simulation of the ultrasonic excitation modes was modeled in Ansys software. The simulation results of the sound pressure distribution in the flow channel show that (1, 1) and (2, 1) are successfully excited. The micro-separator with 8 mm width and 0.2 mm high flow channel was fabricated on silicon on insulator (SOI) by micro-processing technology to form a perfect reflection layer of the separator. An experimental platform was established and the results show that both excitation methods can achieve the separation of suspended particles with high-through of 100 μL/min. In the experiment of (1, 1) excitation method, it can be seen that most of the particles converge in the center of the separation cavity into a large bunch, and in the experiment of (2, 1) excitation method, the particles mainly converge on both sides of the separation chamber. Both methods can successfully separate suspended particles out of the fluid.
Similar content being viewed by others
REFERENCES
Ozcelik, A., Rufo, J., Feng Guo, Yuyang Gu, Peng Li, Lata, J., and Huang, T.J., Nat. Methods, 2018, vol. 15, no. 12, p. 1021. https://doi.org/10.1038/s41592-018-0222-9
Kandemir, M.H., Wagterveld, R.M., Yntema, D.R., and Keesman, K.J., Sci. Rep., 2019, vol. 9, p.7156. https://doi.org/10.1038/s41598-019-43711-8
Kotz, K.T., Dubay, R., Berlin, D., and Fiering, J., Cytotherapy, 2017, vol. 19, no. 5, p. S20.
Vakarelski, I.U., Li, E.Q., Abdel-Fattah, A.I., and Thoroddsen, S.T., Colloids Surf., A, 2016, vol. 506, p. 138. https://doi.org/10.1016/j.colsurfa.2016.06.013
Dow, P., Kotz, K., Gruszka, S., Holder, J., and Fiering, J., Lab Chip, 2018, vol. 18, no. 6, p. 923. https://doi.org/10.1039/c7lc01180f
Karlsen, J.T., Augustsson, P., and Bruus, H., Phys. Rev. Lett., 2016, vol. 117, no. 11, article no. 114504. https://doi.org/10.1103/PhysRevLett.117.114504
Plouffe, B.D., Murthy, S.K., and Lewis, L.H., Rep. Prog. Phys., 2015, vol. 78, no. 1, article no. 016601. https://doi.org/10.1088/0034-4885/78/1/016601
Ding, X.Y., Li, P., Lin, S.C.S., Stratton, Z.S., Nama, N., Guo, F., Slotcavage, D., Mao, X.L., Shi, J.J., Costanzo, F., and Huang, T.J., Lab Chip, 2013, vol. 13, no. 18, article no. 3626. https://doi.org/10.1039/c3lc50361e
Li, P., Mao, Z.M., Peng, Z.L., Zhou, L.L., Chen, Y.C., Huang, P.H., Truica, C.I., Drabick, J.J., El-Deiry, W.S., Dao, M., Suresh, S., and Huang, T.J., Proc. Natl. Acad. Sci. U. S. A., 2015, vol. 112, no. 16, p. 4970. https://doi.org/10.1073/pnas.1504484112
Wu, M.X., Ozcelik, A., Rufo, J., Wang, Z.Y., Fang, R., and Huang, T.J., Microsyst. Nanoeng., 2019, vol. 5, article no. 32. https://doi.org/10.1038/s41378-019-0064-3
Chen, Y.C., Wu, M.X., Ren, L.Q., Liu, J.Y., Whitley, P.H., Wang, L., and Huang, T.J., Lab Chip, 2016, vol. 16, no. 18, p. 3466. https://doi.org/10.1039/c6lc00682e
Antfolk, M., Magnusson, C., Augustsson, P., Lija, H., and Laurell, T., Anal. Chem., 2015, vol. 87, no. 18, p. 9322. https://doi.org/10.1021/acs.analchem.5b02023
Adams, J.D., Ebbesen, C.L., Barnkob, R., Yang, A.H.J., Soh, H.T., and Bruus, H., J. Micromech. Microeng., 2012, vol. 22, no. 7, article no. 075017. https://doi.org/10.1088/0960-1317/22/7/075017
Ding, X.Y., Peng, Z.L., Lin, S.C.S., Geri, M., Li, S.X., Li, P., Chen, Y.C., Dao, M., Suresh, S., and Huang, T.J., Proc. Natl. Acad. Sci. U. S. A., 2014, vol. 111, no. 36, p. 12992. https://doi.org/10.1073/pnas.1413325111
Jakobsson, O., Antfolk, M., and Laurell, T., Anal. Chem., 2014, vol. 86, no. 12, p. 6111. https://doi.org/10.1021/ac5012602
Laurell, T., Petersson, F., and Nilsson, A., Chem. Soc. Rev., 2007, vol. 36, no. 3, p. 492. https://doi.org/10.1039/b601326k
Wang, Y.X., Ding, J.X., and Hua, C.H., Proc. 2009 IEEE Int. Ultrasonics Symposium, Roma, 2009, p. 2529.
Benes, E., Groschl, M., and Nowotny, H., Proc. 2001 IEEE Int. Ultrasonics Symposium, Atlanta, GA, 2001, p. 649.
Cheeke, J.D. and Zagzebski, J., Am. J. Phys., 2004, vol. 72, no. 5, p. 719. https://doi.org/10.1119/1.1645288
ACKNOWLEDGMENTS
The authors wish to thank the National Natural Science Foundation of China for financial support under grant no. 50675031 and the 2019 school-level scientific research project of Chengdu University of Technology 2019ZR014.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hua, C., Ding, J. High-throughput Double-mode Ultrasonic Micro-separator Based on 2D Normal Mode. Instrum Exp Tech 64, 496–502 (2021). https://doi.org/10.1134/S0020441221030179
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0020441221030179