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Application of 3D Bioprinters for Dental Pulp Regeneration and Tissue Engineering (Porous architecture)

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Abstract

One of the well-known ways to produce porous scaffolds or special three-dimensional (3D) micro-nanostructures is using the 3D printing technique. This technique requires a suitable computerized model of the scaffold using computer-aided design software or the computed tomography. The 3D printer fabricates a product by using a digital file and creates a layer-by-layer physical sample. Integrating different technologies and materials into one operational procedure can produce 3D tissue engineering scaffolds with enhanced properties. There are different tissue engineering strategies, including cell-based, factor-based, and scaffold-based strategies. In scaffold-based tissue engineering, 3D scaffolds are one of the most important applications of 3D printers, especially in medical science. In this article, a review of 3D printers, suitable for the production of soft and hard tissue engineering with different technologies is performed and several 3D printing techniques are described. Moreover, the pros and cons, and limitations of the 3D printing technique are discussed.

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Acknowledgements

The authors would like to extend their gratitude for the support provided by the New Technology Research Centre, Tehran, and Iran. This research work was the result of joint support of the clinical scientist program, Isfahan University of Medical Sciences and the New Technology Research Centre, and Islamic Azad University, Tehran, Iran.

Funding

This work was not supported or grants by any Science Foundation. The work is self-funded and the funders had a role in study design, data collection, and analysis, decision to publish, or preparation of the manuscript.

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Authors and Affiliations

  1. Department of Endodontics, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran

    Pedram Iranmanesh & Abbasali Khademi

  2. Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran

    Athena Ehsani, Azadeh Asefnejad & Maryam Soleimani

  3. Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK

    Sheyda Shahriari

  4. Industrial Engineering Department, Girne American University, Via Mersin 10, TRNC, Kyrenia, Turkey

    Mazyar Ghadiri Nejad

  5. New Technologies Research Center, Amirkabir University of Technology, 15875-4413, Tehran, Iran

    Saeed Saber-Samandari & Amirsalar Khandan

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  1. Pedram Iranmanesh
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  2. Athena Ehsani
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  3. Abbasali Khademi
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  4. Azadeh Asefnejad
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  6. Maryam Soleimani
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  7. Mazyar Ghadiri Nejad
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  8. Saeed Saber-Samandari
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  9. Amirsalar Khandan
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Contributions

All the researchers participated in the design of this study. Asefnejad organize the work and collect the information and help in writing the manuscript. Ehsani and Khandan write the first draft of the manuscript. Iranmanesh perform the revison on dental materials. Ghadirinejad and Shahriari conduct the revision of language and referencing. Khandan and Asefnejad performed the statistical analysis. Samandari collected important background information. Khandan and Ehsani drafted the manuscript. All authors read and approved the final manuscript.

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Correspondence to Abbasali Khademi.

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Iranmanesh, P., Ehsani, A., Khademi, A. et al. Application of 3D Bioprinters for Dental Pulp Regeneration and Tissue Engineering (Porous architecture). Transp Porous Med 142, 265–293 (2022). https://doi.org/10.1007/s11242-021-01618-x

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