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Blisters on your fingers

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Journal of Cell Communication and Signaling Aims and scope

Abstract

Mesenchymal progenitor cells play a key role in fibrogenesis. An exciting paper was recently published showed that blister fluid from the skin patients with the autoimmune connective tissue disease scleroderma (systemic sclerosis, SSc) preferentially activated mesenchymal progenitor cells (Taki et al. in Arthritis Rheumatol 72(8):1361–1374, 2020). These data provide new and invaluable insights into the complex interactions in the connective tissue microenvironment that ultimately result in persistent, pathological fibrosis.

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Authors and Affiliations

  1. College of Dentistry, University of Saskatchewan, 105 Wiggins Road, Saskatoon, SK, Canada

    Andrew Leask

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  1. Andrew Leask
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Correspondence to Andrew Leask.

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Leask, A. Blisters on your fingers. J. Cell Commun. Signal. 15, 465–466 (2021). https://doi.org/10.1007/s12079-021-00626-2

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  • DOI: https://doi.org/10.1007/s12079-021-00626-2

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