Abstract
This is a cross-sectional study with data and biological material collection from vineyard farmers in southern Brazil. An interview was carried out through a questionnaire developed according to the reference guide of the state government. Plasma and urine samples were screened for Aluminum, Chromium, Manganese, Copper, Nickel, Cobalt, Zinc, Arsenic, Selenium, Cadmium, Antimony, Barium, Mercury, Lead and Uranium, with a technique for fast determination of these elemental contents in biological material utilizing dynamic reaction cell inductively coupled mass spectrometry. Principal component analysis was used to identify associations between these elemental contents in biological samples and the information obtained from the interviews. The farmers showed some trace elements in plasma and urine at a higher concentration than unexposed populations from other studies. This study highlights recent findings of trace elements in biological material and their association with characteristics of pesticide use. In addition, it also contributes to the gap in the literature regarding trace elements content in plasma and urine of workers exposed to pesticides.
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The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
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Acknowledgements
We are thankful to National Council for Scientific and Technological Development (CNPQ), Institute of Rural Development of Paraná (IDR PARANÁ), Marialva, Paraná, Brazil, and Secretaria de Saúde de Marialva for the support.
Funding
This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) – Finance Code 001. This study was supported by Secretaria de Estado de Ciência, Tecnologia e Ensino Superior (SETI, Curitiba, Paraná, Brasil), Unidade de Gestão do Fundo do Paraná (SETI/UGF, Curitiba, Paraná, Brasil) Grant number [35591.433.38503.22082016]; Programa de Extensão "Universidade Sem Fronteiras" (USF).
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All authors contributed to the study’s conception and design. Material preparation, data collection, and analysis were performed by RSL, RGA, DH, SC, and SBN. Investigation and methodology were performed by RSL, FPP, TP, and BLB. Data analysis was performed by RSL and LRM. Funding acquisition was performed by MLFO, MMJ, and SAGM. Data curation, project administration, resources, and supervision were performed by MLFO and SAGM. The first draft of the manuscript was written by RSL and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Approval was obtained from the ethics committee of the State University of Maringa. The procedures used in this study are in accordance with the tenets of the Declaration of Helsinki. Informed consent was obtained from all individual participants included in the study.
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Lini, R.S., Aguera, R.G., Hoeltgebaum, D. et al. Elemental plasma content and urinary excretion in vineyard farmers occupationally exposed to pesticides in southern Brazil. Environ Sci Pollut Res 28, 51841–51853 (2021). https://doi.org/10.1007/s11356-021-14384-6
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DOI: https://doi.org/10.1007/s11356-021-14384-6