Clinical ResearchIntercountry Differences in Guideline-Directed Medical Therapy and Outcomes Among Patients With Heart Failure
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Central Illustration
Key Words
Canada
GUIDE-IT
guideline-directed medical therapy
heart failure and reduced ejection fraction
United States
Abbreviations and Acronyms
ACE
angiotensin-converting enzyme
ARB
angiotensin II receptor blocker
CI
confidence interval
GDMT
guideline-directed medical therapy
HF
heart failure
HFrEF
heart failure with reduced ejection fraction
HR
hazard ratio
IQR
interquartile range
MRA
mineralocorticoid receptor antagonist
NT-proBNP
N-terminal pro–B-type natriuretic peptide
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John Teerlink, MD, served as the Guest Editor for this paper.
The authors attest they are in compliance with human studies committees and animal welfare regulations of the authors’ institutions and Food and Drug Administration guidelines, including patient consent where appropriate. For more information, visit the Author Center.
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Drs. Ezekowitz and Desai are joint senior authors.
© 2021 by the American College of Cardiology Foundation. Published by Elsevier.