Acquired decrease of the C3b/C4b receptor (CR1, CD35) and increased C4d deposits on erythrocytes from ICU COVID-19 patients
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Abbreviations
CR1
complement receptor type 1
CR1/E
complement receptor type 1 per erythrocyte
CR1/E%
complement receptor type 1 per erythrocyte as percentage of the CR1/E density expected from the CR1 density polymorphism genotype of the patient
C3
complement fragment 3
C4
complement fragment 4
C1q
complement component 1q
C1r
complement component 1r
C1s
complement component 1s
C3a
complement component 3a
C3b
complement component 3b
C4a
complement component 4a
C4d
complement component 4d
C5a
complement component 5a
DAT
direct antiglobulin test
E
erythrocytes
FITC
fluorescein iso-thio-cyanate
HbA1c
glycosylated hemoglobin type A
ICU
intensive care unit
IgG
immunoglobulin G
IgM
immunoglobulin M
MBL
mannan binding lectin
MASP1
mannan binding lectin serine protease1
PE
phyco-erythrin
RFLP
restriction fragment length polymorphism
Sa02
oxygen saturation
SCR
short consensus repeat
SLE
systemic lupus erythematosus
Keywords
COVID-19
Complement
CR1
CD35
C3
C4
Erythrocytes
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© 2021 The Authors. Published by Elsevier GmbH.