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The Pangenomic Classification of Pituitary Neuroendocrine Tumors: Quality Histopathology is Required for Accurate Translational Research

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References

  1. Neou M, Villa C, Armignacco R et al. Pangenomic Classification of Pituitary Neuroendocrine Tumors. Cancer Cell 2020; 37(1):123-134.

    Article  CAS  Google Scholar 

  2. Asa SL, Ezzat S. The cytogenesis and pathogenesis of pituitary adenomas. Endocr Rev 1998; 19:798-827.

    CAS  PubMed  Google Scholar 

  3. Mete O, Cintosun A, Pressman I, Asa SL. Epidemiology and biomarker profile of pituitary adenohypophysial tumors. Mod Pathol 2018; 31(6):900-909.

    Article  CAS  Google Scholar 

  4. Mete O, Asa SL. Structure, Function, and Morphology in the Classification of Pituitary Neuroendocrine Tumors: the Importance of Routine Analysis of Pituitary Transcription Factors. Endocr Pathol 2020; 31(4):330-336.

    Article  Google Scholar 

  5. Mete O, Kefeli M, Caliskan S, Asa SL. GATA3 immunoreactivity expands the transcription factor profile of pituitary neuroendocrine tumors. Mod Pathol 2019; 32(4):484-489.

    Article  CAS  Google Scholar 

  6. Nishioka H, Inoshita N, Mete O et al. The Complementary Role of Transcription Factors in the Accurate Diagnosis of Clinically Nonfunctioning Pituitary Adenomas. Endocr Pathol 2015; 26(4):349-355.

    Article  CAS  Google Scholar 

  7. Asa SL, Mete O. Cytokeratin profiles in pituitary neuroendocrine tumors. Hum Pathol 2021; 107:87-95.

    Article  CAS  Google Scholar 

  8. Asa SL, Puy LA, Lew AM, Sundmark VC, Elsholtz HP. Cell type-specific expression of the pituitary transcription activator Pit-1 in the human pituitary and pituitary adenomas. J Clin Endocrinol Metab 1993; 77:1275-1280.

    CAS  PubMed  Google Scholar 

  9. Asa SL, Bamberger A-M, Cao B, Wong M, Parker KL, Ezzat S. The transcription activator steroidogenic factor-1 is preferentially expressed in the human pituitary gonadotroph. J Clin Endocrinol Metab 1996; 81:2165-2170.

    CAS  PubMed  Google Scholar 

  10. Mete O, Alshaikh OM, Cintosun A, Ezzat S, Asa SL. Synchronous Multiple Pituitary Neuroendocrine Tumors of Different Cell Lineages. Endocr Pathol 2018; 29(4):332-338.

    Article  CAS  Google Scholar 

  11. Kovacs K, Asa SL, Horvath E et al. Null cell adenomas of the pituitary: Attempts to resolve their cytogenesis. In: Lechago J, Kameya T, editors. Endocrine Pathology Update. New York: Field and Wood, 1990: 17-31.

    Google Scholar 

  12. Yamada S, Asa SL, Kovacs K. Oncocytomas and null cell adenomas of the human pituitary: morphometric and in vitro functional comparison. Virchows Arch [A] 1988; 413:333-339.

    Article  CAS  Google Scholar 

  13. Asa SL, Gerrie BM, Singer W, Horvath E, Kovacs K, Smyth HS. Gonadotropin secretion in vitro by human pituitary null cell adenomas and oncocytomas. J Clin Endocrinol Metab 1986; 62:1011-1019.

    Article  CAS  Google Scholar 

  14. Drummond J, Roncaroli F, Grossman AB, Korbonits M. Clinical and Pathological Aspects of Silent Pituitary Adenomas. J Clin Endocrinol Metab 2019; 104(7):2473-2489.

    Article  Google Scholar 

  15. Balogun JA, Monsalves E, Juraschka K et al. Null cell adenomas of the pituitary gland: an institutional review of their clinical imaging and behavioral characteristics. Endocr Pathol 2015; 26(1):63-70.

    Article  Google Scholar 

  16. Almeida JP, Stephens CC, Eschbacher JM et al. Clinical, pathologic, and imaging characteristics of pituitary null cell adenomas as defined according to the 2017 World Health Organization criteria: a case series from two pituitary centers. Pituitary 2019; 22(5):514-519.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, University Health Network and University of Toronto, Toronto, Canada

    Ozgur Mete

  2. Department of Medicine, University Health Network and University of Toronto, Toronto, Canada

    Shereen Ezzat

  3. Department of Pathology, University of California, San Francisco, San Francisco, CA, USA

    Arie Perry

  4. Department of Neurosurgery, Toranomon Hospital, Tokyo Neurological Center, Tokyo, Japan

    Shozo Yamada

  5. Hypothalamic and Pituitary Center, Moriyama Memorial Hospital, Tokyo, Japan

    Shozo Yamada

  6. Department of Pathology, University of Insubria, Varese, Italy

    Silvia Uccella

  7. Centre for Endocrinology, Barts and the London School of Medicine, London, UK

    Ashley B. Grossman

  8. Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK

    Ashley B. Grossman

  9. Department of Pathology, University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, OH, USA

    Sylvia L. Asa

Authors
  1. Ozgur Mete
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  2. Shereen Ezzat
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  3. Arie Perry
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  4. Shozo Yamada
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  5. Silvia Uccella
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  6. Ashley B. Grossman
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  7. Sylvia L. Asa
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Correspondence to Ozgur Mete.

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Mete, O., Ezzat, S., Perry, A. et al. The Pangenomic Classification of Pituitary Neuroendocrine Tumors: Quality Histopathology is Required for Accurate Translational Research. Endocr Pathol 32, 415–417 (2021). https://doi.org/10.1007/s12022-021-09671-4

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  • DOI: https://doi.org/10.1007/s12022-021-09671-4

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