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DEVELOPMENTAL BIOLOGY

3D in vitro models of human blastocysts

Two independent teams have developed the first in vitro human blastocysts.

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Research papers

  • Yu, L. et al. Blastocyst-like structures generated from human pluripotent stem cells. Nature 591, 620–626 (2021).

    Article  CAS  Google Scholar 

  • Liu, X. et al. Modelling human blastocysts by reprogramming fibroblasts into iBlastoids. Nature 591, 627–632 (2021).

    Article  CAS  Google Scholar 

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Correspondence to Madhura Mukhopadhyay.

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Mukhopadhyay, M. 3D in vitro models of human blastocysts. Nat Methods 18, 445 (2021). https://doi.org/10.1038/s41592-021-01158-8

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  • DOI: https://doi.org/10.1038/s41592-021-01158-8

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